Figure 5

Inhibitory effects of CZ on blood glucose after maltose loading in normal rats. The normal rats fasted for 16 h received maltose (2 g/kg body wt; p.o.) and dose of CZ (300 mg/kg body wt; p.o.) by gastric intubation. Control group received maltose (2 g/kg body wt; p.o.) alone, and the drug control group received maltose (2 g/kg body wt; p.o.) plus acarbose (5 mg/kg). Blood glucose was measured at 0, 30, 60 and 120 min after food administration. A. The glycemic response curve in normal rats after maltose challenge. B. The incremental AUC_{0-120 min} in normal rats after maltose administration. Data are expressed as the mean ± S.E, n = 6. *, P < 0.05 vs. control; **, P < 0.01 vs. control; ***, P < 0.001 vs. control.