Inhibitory effect of CZ on blood glucose after sucrose loading in diabetic rats. The diabetic rats fasted for 16 h received sucrose (2 g/kg body wt; p.o.) and a dose of CZ (300 mg/kg body wt; p.o.) by gastric intubations. Control animals were given only sucrose (2 g/kg body wt; p.o.) and the drug control group received sucrose (2 g/kg body wt; p.o.) plus acarbose (5 mg/kg). Blood glucose was monitored at 0, 30, 60 and 120 min after food administration. A. The glycemic response curve in diabetic rats after sucrose challenge. B. The incremental AUC0-120 min in diabetic rats after sucrose administration. Data are expressed as the mean ± S.E, n = 6. *, P < 0.05 vs. control; **, P < 0.01 vs. control; ***, P < 0.001 vs. control.