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Table 4 Diacylglycerol (DAG) levels in the liver, gastrocnemius mucle, heart, epididymal and inguinal adipose tissue and kidneys of high-fat fed mice with dietary krill oil (HFKO) supplementation

From: Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice

Tissue and DAGs N (pmol/mg) HF (pmol/mg) HFKO1.25 (pmol/mg) HFKO2.5 (pmol/mg) HFKO5 (pmol/mg)
Liver      
18:1-20:4 10.8 ± 2.3 12.1 ± 2.8 7.7 ± 0.5 7.1 ± 1.9 7.3 ± 1.2
16:0-20:4 8.9 ± 2.4 8.1 ± 1.0 4.3 ± 1.0 4.2 ± 1.2 5.9 ± 1.7
18:0-20:4 7.6 ± 1.7 7.7 ± 1.3 11.2 ± 2.3 10.5 ± 2.4 17.4 ± 0.9*
Gastrocnemius      
18:1-20:4 25.0 ± 3.8 17.1 ± 3.3 11.5 ± 2.5 12.1 ± 3.3 17.7 ± 1.8
16:0-20:4 4.9 ± 1.1 8.7 ± 2.3# 3.4 ± 0.7* 4.2 ± 0.5* 3.7 ± 0.5*
18:0-20:4 43.6 ± 3.8 40.0 ± 7.0 27.1 ± 6.0 24.9 ± 2.1 20.4 ± 1.3*
Heart      
18:1-20:4 3.0 ± 0.2 7.2 ± 2.1 7.1 ± 0.7 5.1 ± 0.4 7.1 ± 1.5
16:0-20:4 0.4 ± 0.1 1.2 ± 0.4 0.5 ± 0.2 0.7 ± 0.2 0.4 ± 0.1
18:0-20:4 11.3 ± 0.6 21.1 ± 4.2# 11.8 ± 1.6* 13.2 ± 1.9* 10.1 ± 2.5*
Epididymal adipose tissue      
18:1-20:4 12.3 ± 1.9 37.0 ± 2.2### 4.3 ± 0.4*** 4.7 ± 0.7*** 2.9 ± 1.1***
18:0-20:4 13.9 ± 4.4 16.9 ± 2.2 37 ± 0.5*** 6.8 ± 2.7* 3.0 ± 1.5**
Inguinal adipose tissue      
18:1-20:4 23.3 ± 3.26 16.3 ± 1.2# 9.7 ± 2.9 7.5 ± 1.4* 5.9 ± 0.5**
16:0-20:4 - 6.8 ± 0.8### 2.4 ± 0.4*** 2.4 ± 0.4*** 3.2 ± 0.2***
18:0-20:4 49.8 ± 12.6 31.3 ± 6.6 20.6 ± 2.2 12.5 ± 2.5 12.4 ± 1.6
Kidney      
18:1-20:4 2.0 ± 0.4 6.6 ± 1.4## 7.0 ± 0.7 3.2 ± 0.5* 5.1 ± 0.7
16:0-20:4 1.9 ± 0.1 1.3 ± 0.2 0.8 ± 0.2 1.1 ± 0.2 1.3 ± 0.2
18:0-20:4 10.4 ± 1.5 23.8 ± 5.3# 24.1 ± 1.4 21.3 ± 5.1 24.5 ± 1.3
  1. Data are means ± SEM of separate determinations in N = 4-5 mice. # P < 0.05, ## P < 0.01 and ### P < 0.001 HF vs N; * P < 0.05, **P < 0.01 and *** P < 0.001 HFKO1.25-2.5-5 vs HF.