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Table 4 Diacylglycerol (DAG) levels in the liver, gastrocnemius mucle, heart, epididymal and inguinal adipose tissue and kidneys of high-fat fed mice with dietary krill oil (HFKO) supplementation

From: Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice

Tissue and DAGs

N (pmol/mg)

HF (pmol/mg)

HFKO1.25 (pmol/mg)

HFKO2.5 (pmol/mg)

HFKO5 (pmol/mg)

Liver

     

18:1-20:4

10.8 ± 2.3

12.1 ± 2.8

7.7 ± 0.5

7.1 ± 1.9

7.3 ± 1.2

16:0-20:4

8.9 ± 2.4

8.1 ± 1.0

4.3 ± 1.0

4.2 ± 1.2

5.9 ± 1.7

18:0-20:4

7.6 ± 1.7

7.7 ± 1.3

11.2 ± 2.3

10.5 ± 2.4

17.4 ± 0.9*

Gastrocnemius

     

18:1-20:4

25.0 ± 3.8

17.1 ± 3.3

11.5 ± 2.5

12.1 ± 3.3

17.7 ± 1.8

16:0-20:4

4.9 ± 1.1

8.7 ± 2.3#

3.4 ± 0.7*

4.2 ± 0.5*

3.7 ± 0.5*

18:0-20:4

43.6 ± 3.8

40.0 ± 7.0

27.1 ± 6.0

24.9 ± 2.1

20.4 ± 1.3*

Heart

     

18:1-20:4

3.0 ± 0.2

7.2 ± 2.1

7.1 ± 0.7

5.1 ± 0.4

7.1 ± 1.5

16:0-20:4

0.4 ± 0.1

1.2 ± 0.4

0.5 ± 0.2

0.7 ± 0.2

0.4 ± 0.1

18:0-20:4

11.3 ± 0.6

21.1 ± 4.2#

11.8 ± 1.6*

13.2 ± 1.9*

10.1 ± 2.5*

Epididymal adipose tissue

     

18:1-20:4

12.3 ± 1.9

37.0 ± 2.2###

4.3 ± 0.4***

4.7 ± 0.7***

2.9 ± 1.1***

18:0-20:4

13.9 ± 4.4

16.9 ± 2.2

37 ± 0.5***

6.8 ± 2.7*

3.0 ± 1.5**

Inguinal adipose tissue

     

18:1-20:4

23.3 ± 3.26

16.3 ± 1.2#

9.7 ± 2.9

7.5 ± 1.4*

5.9 ± 0.5**

16:0-20:4

-

6.8 ± 0.8###

2.4 ± 0.4***

2.4 ± 0.4***

3.2 ± 0.2***

18:0-20:4

49.8 ± 12.6

31.3 ± 6.6

20.6 ± 2.2

12.5 ± 2.5

12.4 ± 1.6

Kidney

     

18:1-20:4

2.0 ± 0.4

6.6 ± 1.4##

7.0 ± 0.7

3.2 ± 0.5*

5.1 ± 0.7

16:0-20:4

1.9 ± 0.1

1.3 ± 0.2

0.8 ± 0.2

1.1 ± 0.2

1.3 ± 0.2

18:0-20:4

10.4 ± 1.5

23.8 ± 5.3#

24.1 ± 1.4

21.3 ± 5.1

24.5 ± 1.3

  1. Data are means ± SEM of separate determinations in N = 4-5 mice. # P < 0.05, ## P < 0.01 and ### P < 0.001 HF vs N; * P < 0.05, **P < 0.01 and *** P < 0.001 HFKO1.25-2.5-5 vs HF.