Skip to main content

Table 4 Fasting Glucose, Insulin and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR)1

From: Reduced viscosity Barley β-Glucan versus placebo: a randomized controlled trial of the effects on insulin sensitivity for individuals at risk for diabetes mellitus

Parameter

Visit

Placebo

N = 14

3 g/d BBG

N = 15

6 g/d BBG

N = 15

p-value2

Pairwise

Comparisons3

Fasting Plasma Glucose (mg/dL)

Week 0

102.4 (2.4)

103.7 (3.9)

99.1 (2.3)

0.775 (r)

3 g/d: 0.977;

6 g/d: 0.833

 

Week 12

110.1 (4.4)

112.0 (7.6)

100.6 (3.1)

  
 

Change

7.6 (4.7)

8.3 (7.3)

1.5 (3.0)

0.399 (r)

3 g/d: 0.577;

6 g/d: 0.305

Fasting Insulin (uIU/mL)

Week 0

6.5 (1.1)

8.7 (1.6)

8.3 (1.6)

0.752 (r)

3 g/d: 0.671;

6 g/d: 0.856

 

Week 12

8.6 (1.8)

8.3(1.6)

6.7 (1.3)

  
 

Change

2.1 (1.2)

-0.4 (.8)

-1.6 (1.0)

0.014 (r)

3 g/d: 0.091;

6 g/d: 0.008

HOMA-IR

Week 0

1.7 (0.3)

2.3 (0.5)

2.1 (0.4)

0.834 (r)

3 g/d: 0.771;

6 g/d: 0.952

 

Week 12

2.4 (0.5)

2.3 (0.5)

1.7 (0.3)

  
 

Change

0.7 (0.3)

-0.0 (0.3)

-0.4 (0.3)

0.025 (r)

3 g/d: 0.130;

6 g/d: 0.014

Matsuda Index

Week 0

16.0 (2.6)

18.1 (4.1)

16.7 (3.8)

  
 

Week 12

14.1 (3.4)

17.4 (4.7)

17.5 (3.7)

  
 

%

Change

-13.4 (9.4)

-3.3 (10.9)

18.1 (12.2)

0.928 (r)

3 g/d: 0.901;

6 g/d: 0.949

  1. Values presented are Mean (Standard Error of Mean); Change = Change from Week 0 to 12
  2. 1 Data represented includes only subjects with end of study values
  3. 2P-values generated from final analysis of variance model; (r) indicates values were ranked prior to analysis.
  4. 3Pairwise comparisons to Placebo derived by Dunnett's procedure