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Table 4 Fasting Glucose, Insulin and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR)1

From: Reduced viscosity Barley β-Glucan versus placebo: a randomized controlled trial of the effects on insulin sensitivity for individuals at risk for diabetes mellitus

Parameter Visit Placebo N = 14 3 g/d BBG N = 15 6 g/d BBG N = 15 p-value2 Pairwise Comparisons3
Fasting Plasma Glucose (mg/dL) Week 0 102.4 (2.4) 103.7 (3.9) 99.1 (2.3) 0.775 (r) 3 g/d: 0.977; 6 g/d: 0.833
  Week 12 110.1 (4.4) 112.0 (7.6) 100.6 (3.1)   
  Change 7.6 (4.7) 8.3 (7.3) 1.5 (3.0) 0.399 (r) 3 g/d: 0.577; 6 g/d: 0.305
Fasting Insulin (uIU/mL) Week 0 6.5 (1.1) 8.7 (1.6) 8.3 (1.6) 0.752 (r) 3 g/d: 0.671; 6 g/d: 0.856
  Week 12 8.6 (1.8) 8.3(1.6) 6.7 (1.3)   
  Change 2.1 (1.2) -0.4 (.8) -1.6 (1.0) 0.014 (r) 3 g/d: 0.091; 6 g/d: 0.008
HOMA-IR Week 0 1.7 (0.3) 2.3 (0.5) 2.1 (0.4) 0.834 (r) 3 g/d: 0.771; 6 g/d: 0.952
  Week 12 2.4 (0.5) 2.3 (0.5) 1.7 (0.3)   
  Change 0.7 (0.3) -0.0 (0.3) -0.4 (0.3) 0.025 (r) 3 g/d: 0.130; 6 g/d: 0.014
Matsuda Index Week 0 16.0 (2.6) 18.1 (4.1) 16.7 (3.8)   
  Week 12 14.1 (3.4) 17.4 (4.7) 17.5 (3.7)   
  % Change -13.4 (9.4) -3.3 (10.9) 18.1 (12.2) 0.928 (r) 3 g/d: 0.901; 6 g/d: 0.949
  1. Values presented are Mean (Standard Error of Mean); Change = Change from Week 0 to 12
  2. 1 Data represented includes only subjects with end of study values
  3. 2P-values generated from final analysis of variance model; (r) indicates values were ranked prior to analysis.
  4. 3Pairwise comparisons to Placebo derived by Dunnett's procedure