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Table 2 Serum lipid and inflammatory biomarker measurement of subjects in walnut oil group

From: Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells

 

Lipids

Inflammatory markers

Time (h)

TG

(mg/dL)

TC

(mg/dL)

LDL-C

(mg/dL)

HDL-C

(mg/dL)

TNF-α

(pg/mL)

IL-6

(pg/mL)

CRP

(mg/L)

0

129.5 (15.1)

197.4 (6.2)

130.5 (5.8)

41.1 (2.9)

1.46 (0.43)

1.28 (0.28)

3 (0.75)

1

136.7 (14.6)

210.2 (7.3)

140.3 (6.6)

42.7 (2.9)

2.05 (0.56)

1.29 (0.32)

3.93 (1.23)

2

158.9 (15.7)*

211 (6.5)

138 (5.2)

41.1 (3.3)

1.5 (0.27)

2.05 (0.54)

4.04 (1.07)

4

163.2 (19.5)*

207.3 (6.6)

134.4 (6.1)

40.3 (3.1)

2.14 (0.7)

1.95 (0.38)

3.25 (0.72)

6

133.3 (14.6)

206.3 (6.1)

138.8 (6.1)

40.9 (3.5)

1.95 (0.66)

2.47 (0.36)

3.38 (0.96)

  1. TG: triacylglycerol; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; TNF-α: tumor necrosis factor alpha; IL-6: interleukin 6; CRP: C reactive protein. All values were expressed as mean ± SEM. Inflammatory biomarkers were measured by high sensitive ELISA. The GCRC Core Laboratory at Hershey Medical Center performed the assays for lipids and lipoproteins. LDL-C was calculated using the Friedewald equation [51]. Symbol * indicates a significant difference from baseline.