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Table 2 Serum lipid and inflammatory biomarker measurement of subjects in walnut oil group

From: Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells

  Lipids Inflammatory markers
Time (h) TG (mg/dL) TC (mg/dL) LDL-C (mg/dL) HDL-C (mg/dL) TNF-α (pg/mL) IL-6 (pg/mL) CRP (mg/L)
0 129.5 (15.1) 197.4 (6.2) 130.5 (5.8) 41.1 (2.9) 1.46 (0.43) 1.28 (0.28) 3 (0.75)
1 136.7 (14.6) 210.2 (7.3) 140.3 (6.6) 42.7 (2.9) 2.05 (0.56) 1.29 (0.32) 3.93 (1.23)
2 158.9 (15.7)* 211 (6.5) 138 (5.2) 41.1 (3.3) 1.5 (0.27) 2.05 (0.54) 4.04 (1.07)
4 163.2 (19.5)* 207.3 (6.6) 134.4 (6.1) 40.3 (3.1) 2.14 (0.7) 1.95 (0.38) 3.25 (0.72)
6 133.3 (14.6) 206.3 (6.1) 138.8 (6.1) 40.9 (3.5) 1.95 (0.66) 2.47 (0.36) 3.38 (0.96)
  1. TG: triacylglycerol; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; TNF-α: tumor necrosis factor alpha; IL-6: interleukin 6; CRP: C reactive protein. All values were expressed as mean ± SEM. Inflammatory biomarkers were measured by high sensitive ELISA. The GCRC Core Laboratory at Hershey Medical Center performed the assays for lipids and lipoproteins. LDL-C was calculated using the Friedewald equation [51]. Symbol * indicates a significant difference from baseline.