Effect of chronic exercise training and/or leucine supplementation on body weight changes. (A) Body weight. #, effect of training in fifth week (P = 0.045); + vs week 1 (P < 0.002). (B) Total body weight variation (final - initial body weight). *, effect of diet (P = 0.028); #, effect of training, (P = 0.006). Experimental groups: control diet (REF), diet supplemented with 5% L-leucine (LS), 6 weeks of endurance training (ET) plus standard diet, and diet supplemented with 5% L-leucine plus endurance training (LS+ET). Values are mean ± sem (n = 7-8 rats per group).