Chronic exercise is more efficient than leucine supplementation in reducing adiposity. (A) Body composition (%). #, effect of training (P < 0.019). (B) Epididymal adipocyte volume. #, effect of training (P < 0.005); *, effect of diet, (P < 0.020). (C) Epididymal adipocyte number #, effect of training (P < 0.044). Experimental groups: control diet (REF), diet supplemented with 5% L-leucine (LS), 6 weeks of endurance training (ET) plus standard diet, and diet supplemented with 5% L-leucine plus endurance training (LS+ET). Values are mean ± sem (n = 7-8 rats per group).