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Table 5 Clinical chemistry and biochemical characteristics in overweight women at baseline and after dietary intervention

From: Effect of a conventional energy-restricted modified diet with or without meal replacement on weight loss and cardiometabolic risk profile in overweight women

  MR (n = 34) aMean ± SD C (n = 34) a Mean ± SD MR vs C
  Baseline Week 12 Difference Baseline Week 12 Difference P b
Glucose (mg/dL) 91.8 ± 13.7 92.4 ± 10.9 0.63 ± 10.94 90.7 ± 14.3 88.1 ± 13.1 -2.66 ± 10.74 0.315
HbA1c (%) 5.54 ± 0.63 5.49 ± 0.47 -0.05 ± 0.64 5.63 ± 0.51 5.46 ± 0.48 -0.16 ± 0.61 0.201
TC (mg/dL) 241.2 ± 53.1 224.4 ± 53.2* -16.7 ± 33.7 241.5 ± 34.3 230.3 ± 40.9* -11.2 ± 25.9 0.556
HDL-C (mg/dL) 59.1 ± 16.1 55.3 ± 14.1** -3.7 ± 6.2 59.2 ± 11.5 55.7 ± 10.9* -3.5 ± 5.2 0.864
LDL-C (mg/dL) 157.0 ± 39.7 144.0 ± 38.4** -13.0 ± 18.2 161.4 ± 24.2 152.3 ± 30.8* -9.1 ± 18.7 0.647
TG (mg/dL) 186.4 ± 145.6 161.1 ± 108.0 -25.3 ± 110.4 152.5 ± 83.8 141.6 ± 66.1 -10.9 ± 52.9 0.861
TG/HDL-C 3.59 ± 3.55 3.19 ± 2.49 -0.40 ± 2.44 2.71 ± 1.66 2.62 ± 1.37 -0.09 ± 0.96 0.880
LDL-C/HLD-C 2.81 ± 0.86 2.73 ± 0.86 -0.08 ± 0.33 2.81 ± 0.63 2.79 ± 0.68 -0.02 ± 0.33 0.539
GGT (U/L) 33.5 ± 28.8 27.8 ± 20.1 -5.72 ± 12.91* 27.9 ± 13.3 24.0 ± 10.6 -3.85 ± 4.92** 0.759
Uric acid (mg/dL) 4.82 ± 1.18 4.59 ± 0.94 -0.23 ± 0.70 4.86 ± 1.01 4.75 ± 0.97 0.11 ± 0.66 0.384
Homocysteine
(μmol/L)
11.7 ± 4.1 11.0 ± 2.7 -0.63 ± 2.66 10.3 ± 2.0 11.7 ± 2.7* 1.36 ± 2.65 0.007
Folic acid (μg/L) 10.6 ± 4.9 15.2 ± 5.8** 4.62 ± 5.74 11.1 ± 4.3 12.3 ± 7.2 1.17 ± 6.28 0.005
GFR (mL/min/1.73 m2) 73.6 ± 12.0 73.3 ± 12.1 -0.24 ± 6.50 74.8 ± 8.9 72.5 ± 8.8 -2.27 ± 6.10 0.202
TAC (μmol/L) 266.2 ± 30.8 276.6 ± 38.4 10.4 ± 45.6 280.9 ± 43.0 282.2 ± 45.7 1.3 ± 48.5 0.210
Cortisol (nmol/L) 424.3 ± 142.5 532.1 ± 179.6 107.8 ± 145.6 387.2 ± 164.6 477.4 ± 140.9 90.2 ± 176.0 0.826
TAC/Cortisol (103) 0.70 ± 0.27 0.58 ± 0.20 -0.12 ± 0.27 0.89 ± 0.49 0.65 ± 0.25 -0.24 ± 0.41 0.498
U-sodium (mmol/24 h)c 162.2 ± 64.5 158.2 ± 94,1 -4.0 ± 118.0 158.3 ± 68.1 170.8 ± 81.2 12.5 ± 82.9 0.283
  1. abbreviations used: GFR, glomerular filtration rate; GGT, gamma-glutamyltransferase; HbA1c, glycated haemoglobin; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; TAC, total antioxidative capacity; TC, total cholesterol; TG, triglycerides; U-sodium, urinary sodium
  2. abiochemical measurements with the same method
  3. bp-value: Mann-Whitney-U-test; Wilcoxon-test within groups: *p < 0.05; **p < 0.001
  4. cn = 26 in the MR group and n = 28 in the C group