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Table 5 Clinical chemistry and biochemical characteristics in overweight women at baseline and after dietary intervention

From: Effect of a conventional energy-restricted modified diet with or without meal replacement on weight loss and cardiometabolic risk profile in overweight women

 

MR (n = 34) aMean ± SD

C (n = 34) a Mean ± SD

MR vs C

 

Baseline

Week 12

Difference

Baseline

Week 12

Difference

P b

Glucose (mg/dL)

91.8 ± 13.7

92.4 ± 10.9

0.63 ± 10.94

90.7 ± 14.3

88.1 ± 13.1

-2.66 ± 10.74

0.315

HbA1c (%)

5.54 ± 0.63

5.49 ± 0.47

-0.05 ± 0.64

5.63 ± 0.51

5.46 ± 0.48

-0.16 ± 0.61

0.201

TC (mg/dL)

241.2 ± 53.1

224.4 ± 53.2*

-16.7 ± 33.7

241.5 ± 34.3

230.3 ± 40.9*

-11.2 ± 25.9

0.556

HDL-C (mg/dL)

59.1 ± 16.1

55.3 ± 14.1**

-3.7 ± 6.2

59.2 ± 11.5

55.7 ± 10.9*

-3.5 ± 5.2

0.864

LDL-C (mg/dL)

157.0 ± 39.7

144.0 ± 38.4**

-13.0 ± 18.2

161.4 ± 24.2

152.3 ± 30.8*

-9.1 ± 18.7

0.647

TG (mg/dL)

186.4 ± 145.6

161.1 ± 108.0

-25.3 ± 110.4

152.5 ± 83.8

141.6 ± 66.1

-10.9 ± 52.9

0.861

TG/HDL-C

3.59 ± 3.55

3.19 ± 2.49

-0.40 ± 2.44

2.71 ± 1.66

2.62 ± 1.37

-0.09 ± 0.96

0.880

LDL-C/HLD-C

2.81 ± 0.86

2.73 ± 0.86

-0.08 ± 0.33

2.81 ± 0.63

2.79 ± 0.68

-0.02 ± 0.33

0.539

GGT (U/L)

33.5 ± 28.8

27.8 ± 20.1

-5.72 ± 12.91*

27.9 ± 13.3

24.0 ± 10.6

-3.85 ± 4.92**

0.759

Uric acid (mg/dL)

4.82 ± 1.18

4.59 ± 0.94

-0.23 ± 0.70

4.86 ± 1.01

4.75 ± 0.97

0.11 ± 0.66

0.384

Homocysteine

(μmol/L)

11.7 ± 4.1

11.0 ± 2.7

-0.63 ± 2.66

10.3 ± 2.0

11.7 ± 2.7*

1.36 ± 2.65

0.007

Folic acid (μg/L)

10.6 ± 4.9

15.2 ± 5.8**

4.62 ± 5.74

11.1 ± 4.3

12.3 ± 7.2

1.17 ± 6.28

0.005

GFR (mL/min/1.73 m2)

73.6 ± 12.0

73.3 ± 12.1

-0.24 ± 6.50

74.8 ± 8.9

72.5 ± 8.8

-2.27 ± 6.10

0.202

TAC (μmol/L)

266.2 ± 30.8

276.6 ± 38.4

10.4 ± 45.6

280.9 ± 43.0

282.2 ± 45.7

1.3 ± 48.5

0.210

Cortisol (nmol/L)

424.3 ± 142.5

532.1 ± 179.6

107.8 ± 145.6

387.2 ± 164.6

477.4 ± 140.9

90.2 ± 176.0

0.826

TAC/Cortisol (103)

0.70 ± 0.27

0.58 ± 0.20

-0.12 ± 0.27

0.89 ± 0.49

0.65 ± 0.25

-0.24 ± 0.41

0.498

U-sodium (mmol/24 h)c

162.2 ± 64.5

158.2 ± 94,1

-4.0 ± 118.0

158.3 ± 68.1

170.8 ± 81.2

12.5 ± 82.9

0.283

  1. abbreviations used: GFR, glomerular filtration rate; GGT, gamma-glutamyltransferase; HbA1c, glycated haemoglobin; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; TAC, total antioxidative capacity; TC, total cholesterol; TG, triglycerides; U-sodium, urinary sodium
  2. abiochemical measurements with the same method
  3. bp-value: Mann-Whitney-U-test; Wilcoxon-test within groups: *p < 0.05; **p < 0.001
  4. cn = 26 in the MR group and n = 28 in the C group