MR (n = 34) aMean ± SD | C (n = 34) a Mean ± SD | MR vs C | |||||
---|---|---|---|---|---|---|---|
Baseline | Week 12 | Difference | Baseline | Week 12 | Difference | P b | |
Glucose (mg/dL) | 91.8 ± 13.7 | 92.4 ± 10.9 | 0.63 ± 10.94 | 90.7 ± 14.3 | 88.1 ± 13.1 | -2.66 ± 10.74 | 0.315 |
HbA1c (%) | 5.54 ± 0.63 | 5.49 ± 0.47 | -0.05 ± 0.64 | 5.63 ± 0.51 | 5.46 ± 0.48 | -0.16 ± 0.61 | 0.201 |
TC (mg/dL) | 241.2 ± 53.1 | 224.4 ± 53.2* | -16.7 ± 33.7 | 241.5 ± 34.3 | 230.3 ± 40.9* | -11.2 ± 25.9 | 0.556 |
HDL-C (mg/dL) | 59.1 ± 16.1 | 55.3 ± 14.1** | -3.7 ± 6.2 | 59.2 ± 11.5 | 55.7 ± 10.9* | -3.5 ± 5.2 | 0.864 |
LDL-C (mg/dL) | 157.0 ± 39.7 | 144.0 ± 38.4** | -13.0 ± 18.2 | 161.4 ± 24.2 | 152.3 ± 30.8* | -9.1 ± 18.7 | 0.647 |
TG (mg/dL) | 186.4 ± 145.6 | 161.1 ± 108.0 | -25.3 ± 110.4 | 152.5 ± 83.8 | 141.6 ± 66.1 | -10.9 ± 52.9 | 0.861 |
TG/HDL-C | 3.59 ± 3.55 | 3.19 ± 2.49 | -0.40 ± 2.44 | 2.71 ± 1.66 | 2.62 ± 1.37 | -0.09 ± 0.96 | 0.880 |
LDL-C/HLD-C | 2.81 ± 0.86 | 2.73 ± 0.86 | -0.08 ± 0.33 | 2.81 ± 0.63 | 2.79 ± 0.68 | -0.02 ± 0.33 | 0.539 |
GGT (U/L) | 33.5 ± 28.8 | 27.8 ± 20.1 | -5.72 ± 12.91* | 27.9 ± 13.3 | 24.0 ± 10.6 | -3.85 ± 4.92** | 0.759 |
Uric acid (mg/dL) | 4.82 ± 1.18 | 4.59 ± 0.94 | -0.23 ± 0.70 | 4.86 ± 1.01 | 4.75 ± 0.97 | 0.11 ± 0.66 | 0.384 |
Homocysteine (μmol/L) | 11.7 ± 4.1 | 11.0 ± 2.7 | -0.63 ± 2.66 | 10.3 ± 2.0 | 11.7 ± 2.7* | 1.36 ± 2.65 | 0.007 |
Folic acid (μg/L) | 10.6 ± 4.9 | 15.2 ± 5.8** | 4.62 ± 5.74 | 11.1 ± 4.3 | 12.3 ± 7.2 | 1.17 ± 6.28 | 0.005 |
GFR (mL/min/1.73 m2) | 73.6 ± 12.0 | 73.3 ± 12.1 | -0.24 ± 6.50 | 74.8 ± 8.9 | 72.5 ± 8.8 | -2.27 ± 6.10 | 0.202 |
TAC (μmol/L) | 266.2 ± 30.8 | 276.6 ± 38.4 | 10.4 ± 45.6 | 280.9 ± 43.0 | 282.2 ± 45.7 | 1.3 ± 48.5 | 0.210 |
Cortisol (nmol/L) | 424.3 ± 142.5 | 532.1 ± 179.6 | 107.8 ± 145.6 | 387.2 ± 164.6 | 477.4 ± 140.9 | 90.2 ± 176.0 | 0.826 |
TAC/Cortisol (103) | 0.70 ± 0.27 | 0.58 ± 0.20 | -0.12 ± 0.27 | 0.89 ± 0.49 | 0.65 ± 0.25 | -0.24 ± 0.41 | 0.498 |
U-sodium (mmol/24 h)c | 162.2 ± 64.5 | 158.2 ± 94,1 | -4.0 ± 118.0 | 158.3 ± 68.1 | 170.8 ± 81.2 | 12.5 ± 82.9 | 0.283 |