The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic fatty liver disease (NAFLD) in rats

Table 3 Biochemical indicators of liver function in plasma in control (C) and high fat treated rats fed a diet with fresh soybean oil (FSO), oxidized soybean oil (OSO) and margarine (MG)

Plasma hepato specific enzymes (U/L)
	AST	ALT	ALP	LDH
C	120.5 ± 36.06^a	55.25 ± 4.03 ^a	167.85 ± 28.8^a	410 ± 20 ^a
FSO	145.5 ± 2.38 ^ab	58.5 ± 8.3 ^a	217.71 ± 36.9 ^b	585.5 ± 87.1 ^b
OSO	162.8 ± 15.12 ^b	61 ± 9.02 ^a	269.33 ± 10.21 ^c*	860.5 ± 13.43^c**
MG	207 ± 7.3 ^c++	76.83 ± 9.23 ^b+	248.5 ± 13.7 ^bc	981.5 ± 118.4 ^c

Data are expressed as means ± SD (n = 12 rats per group). C: controls group, FSO: Fresh soybean oil fed group, OSO: oxidized soybean oil fed group, MG: margarine fed group. Alkaline Phosphatase: ALP; Aspartate Transaminase: AST; Alanine Transaminase: ALT; lactate dehydrogenase: LDH
Comparison between groups was made using Duncan's test. Different parameters values followed by different subscript letters (a, b and c) are significantly different between groups. (p < 0.05).
*p < .05, OSO vs. FSO group; **p < .01, OSO vs. FSO group. ⁺p < .05, MG vs OSO group; ⁺⁺p < .05, MG vs. OSO group. Comparison between groups was made using unpaired Student test.

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