| |
L
|
LP
|
LCP
|
LC
|
Con
|
P
|
CP
|
C
|
|---|
|
PTAH
|
26.38 ± 11.65*
|
21.06 ± 10.52 +
|
17.69 ± 5.02 ++
|
15.01 ± 8.52 +++
|
20.07 ± 7.12
|
21.58 ± 13.41 +
|
17.45 ± 4.88 ++
|
21.50 ± 6.92 +
|
|
actin
|
18.87 ± 13.19***
|
24.81 ± 10.39*. +
|
26.81 ± 8.41 ++
|
27.76 ± 8.50 +++
|
31.03 ± 9.00
|
32.69 ± 7.34 +++
|
30.48 ± 8.11 +++
|
27.96 ± 6.25 ++
|
|
elastin
|
25.75 ± 3.93***
|
28.06 ± 3.92***
|
33.73 ± 3.09 +++
|
30.95 ± 8.36 +
|
34.12 ± 7.88
|
33.26 ± 9.02 +++
|
33.78 ± 9.40 +++
|
34.74 ± 5.57 +++
|
|
collagen I
|
12.48 ± 6.77**
|
10.60 ± 8.23***
|
10.85 ± 3.45***
|
7.22 ± 4.76***
|
20.20 ± 12.10
|
22.67 ± 7.18 ++
|
18.67 ± 11.09 +
|
22.11 ± 10.12 ++
|
|
collagen III
|
0.23 ± 0.16*
|
0.20 ± 0.17**
|
0.30 ± 0.18*
|
0.22 ± 0.24**
|
0.50 ± 0.39
|
0.61 ± 0.44 +
|
0.60 ± 0.51 ++
|
0.58 ± 0.43 ++
|
|
total collagen
|
12.75 ± 6.89**
|
10.81 ± 8.36***
|
11.15 ± 3.56***
|
7.44 ± 4.95***
|
20.71 ± 12.27
|
23.29 ± 7.41 +++
|
19.27 ± 11.46 +++
|
22.69 ± 10.38 +++
|
|
van Gieson
|
15.14 ± 6.78***
|
17.45 ± 4.22***
|
17.35 ± 2.08***
|
13.98 ± 4.15***
|
25.57 ± 6.27
|
27.01 ± 5.42 +++
|
25.20 ± 3.34 +++
|
26.08 ± 3.82 +++
|
|
CSA
|
0.77 ± 0.17*
|
0.73 ± 0.19*
|
0.62 ± 0.05 ++
|
0.73 ± 0.13*
|
0.55 ± 0.04
|
0.54 ± 0.07 +
|
0.55 ± 0.09 +
|
0.55 ± 0.03 +
|
|
thickness
|
0.14 ± 0.03*
|
0.14 ± 0.02**
|
0.12 ± 0.01
|
0.14 ± 0.02***
|
0.11 ± 0.01
|
0.10 ± 0.01 ++
|
0.11 ± 0.01 +
|
0.11 ± 0.01 +
|
|
inner diameter
|
1.42 ± 0.09
|
1.51 ± 0.15
|
1.43 ± 0.03
|
1.47 ± 0.12
|
1.54 ± 0.09
|
1.53 ± 0.12
|
1.58 ± 0.11
|
1.49 ± 0.13
|
- The table summarizes the values of the relative content of various proteins in the media of the aorta expressed in% of the total cross sectional area (CSA), which is given in mm2, thickness and inner diameter in mm. Con - control, L - L-NAME induced hypertension, P - piperine, C - curcumin. + p < 0.05, ++ p < 0.01, +++ p < 0.001 versus L; * p < 0.05 versus Con, ** p < 0.01 versus Con, *** p < 0.001 versus Con.
