Table 2 The 15 most strongly up- and down-regulated genes in the liver of growing piglets fed with or without L-carnitine
From: Effect of L-carnitine on the hepatic transcript profile in piglets as animal model
Probe set ID | Gene name (Gene symbol) | FC* | Probe set ID | Gene name (Gene symbol) | FC* |
|---|---|---|---|---|---|
Up-regulated genes | Down-regulated genes | ||||
Ssc.16377.2.A1_at | Glutathione S-transferase A3-3 (GSTA3) | 129.6 | Ssc.27111.1.A1_at | Kelch-like protein 8 (KLHL8) | -7.9 |
Ssc.18484.1.S1_at | Hexokinase D (GCK) | 26.5 | Ssc.30350.1.A1_at | Homeobox protein Meis1 (MEIS1) | -6.6 |
Ssc.14503.1.S1_at | Apolipoprotein A-IV precursor (ApoA4) | 16.6 | Ssc.15845.1.S1_at | Mannose-binding protein C precursor (MBP-C) | -5.8 |
Ssc.13302.1.A1_at | Sentrin-specific protease 6 (SENP6) | 13.0 | Ssc.451.1.A1_at | Insulin-like growth factor binding protein 1 precursor (IGFBP-1) | -5.8 |
Ssc.12965.1.A1_at | Sprouty homolog 3 (SPRY3) | 11.8 | Ssc.22959.1.S1_at | Phosphoenolpyruvate carboxykinase, cytosolic (PCK1) | -5.7 |
Ssc.30459.1.A1_at | R3H domain protein 1 (R3HDM) | 11.3 | Ssc.24758.1.A1_at | estrogen-related receptor gamma isoform 2 (ESRRG) | -5.3 |
Ssc.25850.1.A1_at | Telomerase-binding protein p23 (TEPB) | 9.2 | Ssc.21169.1.S1_at | Synaptic vesicular amine transporter (SLC18A2) | -5.1 |
Ssc.5327.2.A1_at | Cytochrome P450 2J2 (CYP2J2) | 9.2 | Ssc.20502.1.S1_at | Serine/threonine-protein kinase (ULK1) | -5.0 |
Ssc.9177.1.A1_at | SPARC related modular calcium-binding protein 1 precursor (SMOC1) | 8.5 | Ssc.29392.1.A1_at | DRE1 protein (DRE1) | -4.7 |
Ssc.30207.1.A1_at | Ubiquitin carboxyl-terminal hydrolase 1 (USP1) | 8.3 | Ssc.14386.1.A1_at | Cyclin G2 (CCNG2) | -4.7 |
Ssc.8700.1.A1_at | Heterogeneous nuclear ribonucleoprotein M (hnRNP M) | 8.1 | Ssc.29946.1.A1_at | T-cell lymphoma breakpoint-associated target 1 (TCBA1) | -4.2 |
Ssc.8308.1.A1_at | cell adhesion molecule with homology to L1CAM precursor (CHL1) | 7.6 | Ssc.28087.1.A1_at | oxidation resistance 1 (OXR1) | -4.2 |
Ssc.18681.1.A1_at | Metabotropic glutamate receptor 5 precursor GRM5) | 7.5 | Ssc.2274.1.A1_at | Ephrin-A1 precursor (EFNA1) | -4.1 |
Ssc.29205.1.A1_at | Serine/threonine-protein kinase (Nek7) | 7.3 | Ssc.13343.1.A1_at | CD109 (CD109) | -4.1 |
Ssc.18831.1.A1_at | Glutaminase, kidney isoform, mitochondrial precursor (GLS) | 6.8 | Ssc.30210.1.A1_at | Testican-1 precursor (SPOCK) | -4.0 |