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Table 3 Change in Outcome Variables from Baseline to Study Completion by Preload Group

From: Effects of grapefruit, grapefruit juice and water preloads on energy balance, weight loss, body composition, and cardiometabolic risk in free-living obese adults

 

GF Preload

(n = 29)

GFJ Preload

(n = 28)

Water Preload

(n = 28)

 
 

(mean ± SD)

(mean ± SD)

(mean ± SD)

P*

Energy Expenditure

    

RQ (VCO2/VO2)

0.0 ± 0.1

0.0 ± 0.1

0.0 ± 0.1

0.618

REE (kcal)

4.5 ± 27.9

42.1 ± 18.4

- 37.1 ± 22.6

0.151

REE Adjusted (kcal/kg/lbm)

1.6 ± 4.6

1.7 ± 5.1

0.9 ± 5.2

0.078

Body Composition

    

Body Mass Index (kg/m2)

- 1.6 ± 1.6

- 1.9 ± 1.4

- 2.1 ± 1.1

0.523

Waist Circumference (cm)

- 4.0 ± 4.1

- 5.5 ± 5.7

- 5.4 ± 4.8

0.189

Fat Tissue Mass (kg)

- 2.6 ± 2.1

- 2.9 ± 2.9

- 2.5 ± 2.1

0.499

Total Body Fat (%)

- 1.1 ± 1.8

- 1.1 ± 1.9

- 1.2 ± 2.6

0.489

Trunk Fat (%)

- 1.4 ± 2.9

- 1.7 ± 2.6

- 1.2 ± 2.6

0.154

Android Fat (%)

- 1.9 ± 2.4

- 1.2 ± 2.7

- 1.5 ± 3.3

0.239

Gynoid Fat (%)

- 1.5 ± 2.4

- 0.5 ± 2.9

- 0.7 ± 4.5

0.114

Lean Tissue Mass (kg)

- 0.9 ± 2.1

- 1.9 ± 1.9

0.3 ± 2.4

0.127

Lean Tissue Mass (%)

1.1 ± 2.4

0.8 ± 2.0.

1.8 ± 2.6

0.230

BMC (kg)

0.2 ± 0.2

0.0 ± 0.1

0.1 ± 0.2

0.587

Glycemia and Blood Pressure

   

Fasting Glucose (mmol/L)

0.1 ± 0.3

0.1 ± .0.4

0.0 ± 0.4

0.969

Fasting Insulin (uU/mL)

- 0.5 ± 4.7

- 0.3 ± 3.7

- 0.8 ± 7.4

0.691

HOMAIR Score

- 0.2 ± 1.

- 0.1 ± 0.8

- 0.6 ± 1.6

0.095

Systolic Blood Pressure (mmHg)

- 3.1 ± 7.8

-3.1 ± 7.4

- 1.5 ± 6.3

0.922

Diastolic Blood Pressure (mmHg)

- 0.3 ± 8.1

- 3.8 ± 9.1

0.1 ± 8.1

0.565

Lipids

    

Triglycerides (mg/dl)

- 6.7 ± 40.6

- 9.4 ± 31.9

- 4.3 ± 26.2

0.166

Total cholesterol (mg/dl)

3.0 ± 21.3

- 3.2 ± 14.9

2.5 ± 11.1

0.419

LDL cholesterol (mg/dl)

1.8 ± 3.2

5.3 ± 7.9

3.5 ± 7.7

0.498

HDL cholesterol (mg/dl)

3.0 ± 5.2

4.9 ± 7.5**

-2.0 ± 7.2

0.020

HDL to total cholesterol ratio

- 0.2 ± 0.4

- 0.4 ± 0.7**

0.2 ± 0.6

0.025

  1. *P <. 0.05 indicating statistically significant difference by ANCOVA, with baseline value included as covariate. For outcomes showing significant differences by ANCOVA, simple contrasts were conducted within ANCOVA to determine which preloads were significantly different.
  2. ** Significantly different from water preload, P s = 0.017.