Mitigating preventable chronic disease: Progress report of the Cleveland Clinic's Lifestyle 180 program

Nutrition & Metabolism

Table 5 Metabolic outcomes by week^a

Factor	Units	Week One (N = 423)		Week Six (N = 396)		Week 30 (N = 299)
		Mean ± SD	Min - Max	Mean ± SD	Min - Max	Mean ± SD	Min -Max
Glucose	(mg/dL)	108 ± 35^b	67 - 330	102 ± 27^c	62 - 264	103 ± 29	59 - 339
	(mmol/L)	6.0 ± 1.9	3.7 - 18.3	5.7 ± 1.5	3.4 - 14.7	5.7 ± 1.6	3.3 - 18.8
Triglycerides	(mg/dL)	137 ± 81	34 - 839	107 ± 51	34 - 405	109 ± 52^d	32 - 331
	(mmol/L)	1.5 ± 0.9	0.4 - 9.5	1.2 ± 0.6	0.4 - 4.6	1.2 ± 0.6	0.4 - 3.7
Cholesterol	(mg/dL)	187 ± 39	82 - 307	166 ± 36	80 - 294	179 ± 38^d	93 - 290
	(mmol/L)	4.8 ± 1.0	2.1 - 7.9	4.3 ± 0.9	2.1 - 7.6	4.6 ± 1.0	2.4 - 7.5
HDL	(mg/dL)	51 ± 15	24 - 128	50 ± 14	21 - 110	55 ± 16^d	21 - 147
	(mmol/L)	1.3 ± 0.4	0.6 - 3.3	1.3 ± 0.4	0.5 - 2.8	1.4 ± 0.4	0.5 - 3.8
LDL	(mg/dL)	109 ± 33^b	21 - 218	95 ± 31	17 - 225	102 ± 32^e	26 - 215
	(mmol/L)	2.8 ± 0.9	0.5 - 5.6	2.5 ± 0.8	0.4 - 5.8	2.6 ± 0.8	0.7 - 5.6
HgbA1c	(%)	6 ± 1^c	5 - 13	N/A	N/A	6 ± 1^f	5 - 10
Insulin	(microU/dL)	19 ± 18	3 - 134	14 ± 14	1 - 126	13 ± 10	0.5 - 72
	(pmol/L)	131 ± 122	17 - 930	97 ± 97	7 - 877	87 ± 73	3.5 - 500
US-CRP	(mg/mL)	5 ± 8	0.1 - 88	4 ± 5	0.2 - 33	4 ± 6	0.2 - 39
	(nmol/L)	45 ± 66	0.8 - 740	33 ± 45	1.7 - 278	33 ± 48	1.7 - 331

Abbreviations: HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; HgbA1c, hemoglobin A1c; US-CRP, ultra sensitive c-reactive protein. N/A, no required measurement at six weeks.
^a N = 271, 266 and 185 for insulin and N = 285, 273 and 201 for US-CRP at weeks 1, 6, and 30, respectively, since neither parameter measured before June 2009;
^{b, c, d, e, f} indicate 3, 28, 7, 2, 1 and 15 missing data points, respectively.

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