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Table 7 Relationship between baseline conditions and weight change (kg) at 6 and 30 weeks

From: Mitigating preventable chronic disease: Progress report of the Cleveland Clinic's Lifestyle 180 program

Factor Levels N Mean ± SD Difference in means (95% CI)c P valuec
At 6 weeksa:
Diabetes Yes 292 -3.9 ± 2.7 -0.11 (-0.72, 0.50) 0.73
  No 112 -3.7 ± 2.5   
Hyperlipidemia Yes 243 -3.8 ± 2.6 -0.01 (-0.51, 0.54) 0.96
  No 161 -3.8 ± 2.8   
Hypertension Yes 254 -3.9 ± 2.7 0.04 (-0.49, 0.57) 0.88
  No 150 -3.7 ± 2.6   
Metabolic syndrome Yes 234 -4.3 ± 2.7 -0.57 (-1.13, -0.01) 0.048
  No 164 -3.2 ± 2.3   
Obesity (BMI > 30) Yes 324 -4.2 ± 2.7 -1.61 (-2.26, -0.95) < 0.001
  No 80 -2.3 ± 1.9 -0.64 (-1.24, -0.05) d 0.033
At 30 weeksb:
Diabetes Yes 176 -6.4 ± 6.6 1.22 (-0.91, 3.35) 0.26
  No 67 -7.7 ± 7.7   
Hyperlipidemia Yes 151 -6.1 ± 6.7 1.51 (-0.36, 3.39) 0.11
  No 92 -7.9 ± 7.0   
Hypertension Yes 155 -6.7 ± 7.1 0.32 (-1.60, 2.22) 0.74
  No 88 -6.9 ± 6.6   
Metabolic syndrome Yes 135 -7.3 ± 8.1 -0.69 (-2.63, 1.25) 0.48
  No 104 -6.0 ± 4.9   
Obesity (BMI > 30) Yes 185 -7.6 ± 7.4 -3.69 (-5.86, -1.52) < 0.001
  No 58 -4.2 ± 4.1 -2.1 (-4.08, -0.12) d 0.038
  1. a Multivariable model (N = 398) including all five conditions in table plus age, gender, payment options.
  2. b Multivariable model (N = 239) including all five conditions in table plus age, gender, payment options.
  3. c Multivariable model results; significant if P < 0.025; difference in mean change for "Yes" minus "No".
  4. d Difference in mean percent change from baseline.