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Table 7 Relationship between baseline conditions and weight change (kg) at 6 and 30 weeks

From: Mitigating preventable chronic disease: Progress report of the Cleveland Clinic's Lifestyle 180 program

Factor

Levels

N

Mean ± SD

Difference in

means (95% CI)c

P valuec

At 6 weeksa:

Diabetes

Yes

292

-3.9 ± 2.7

-0.11 (-0.72, 0.50)

0.73

 

No

112

-3.7 ± 2.5

  

Hyperlipidemia

Yes

243

-3.8 ± 2.6

-0.01 (-0.51, 0.54)

0.96

 

No

161

-3.8 ± 2.8

  

Hypertension

Yes

254

-3.9 ± 2.7

0.04 (-0.49, 0.57)

0.88

 

No

150

-3.7 ± 2.6

  

Metabolic syndrome

Yes

234

-4.3 ± 2.7

-0.57 (-1.13, -0.01)

0.048

 

No

164

-3.2 ± 2.3

  

Obesity (BMI > 30)

Yes

324

-4.2 ± 2.7

-1.61 (-2.26, -0.95)

< 0.001

 

No

80

-2.3 ± 1.9

-0.64 (-1.24, -0.05) d

0.033

At 30 weeksb:

Diabetes

Yes

176

-6.4 ± 6.6

1.22 (-0.91, 3.35)

0.26

 

No

67

-7.7 ± 7.7

  

Hyperlipidemia

Yes

151

-6.1 ± 6.7

1.51 (-0.36, 3.39)

0.11

 

No

92

-7.9 ± 7.0

  

Hypertension

Yes

155

-6.7 ± 7.1

0.32 (-1.60, 2.22)

0.74

 

No

88

-6.9 ± 6.6

  

Metabolic syndrome

Yes

135

-7.3 ± 8.1

-0.69 (-2.63, 1.25)

0.48

 

No

104

-6.0 ± 4.9

  

Obesity (BMI > 30)

Yes

185

-7.6 ± 7.4

-3.69 (-5.86, -1.52)

< 0.001

 

No

58

-4.2 ± 4.1

-2.1 (-4.08, -0.12) d

0.038

  1. a Multivariable model (N = 398) including all five conditions in table plus age, gender, payment options.
  2. b Multivariable model (N = 239) including all five conditions in table plus age, gender, payment options.
  3. c Multivariable model results; significant if P < 0.025; difference in mean change for "Yes" minus "No".
  4. d Difference in mean percent change from baseline.