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Table 1 Baseline characteristics of the participants

From: Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity

Characteristics of participants

Control

HCF

HP

MIX

p value1

Gender (males/females)

8/10

5/11

7/12

6/10

0.93

Age - yr

55.3 ± 1.9

54.2 ± 3.2

57.4 ± 1.8

55.3 ± 1.9

0.76

Waist circumference - cm

101.6 ± 2.1

101.4 ± 1.9

101.4 ± 2.6

100.6 ± 3.3

0.99

BMI (kg/m2)

31.0 ± 0.8

31.9 ± 0.8

31.4 ± 0.9

31.4 ± 1.0

0.92

M-value (mg·kg-1·min-1)

4.4 ± 0.5

3.8 ± 0.4

4.0 ± 0.4

4.4 ± 0.4

0.67

Fecal SCFA (mM)

     

Acetate (C2)

40.2 ± 3.1

38.8 ± 4.5

39.3 ± 4.4

39.8 ± 3.9

0.88

Propionate (C3)

12.4 ± 1.1

13.3 ± 1.4

13.0 ± 1.3

15.1 ± 1.5

0.64

Butyrate (C4)

12.3 ± 1.5

12.8 ± 2.4

13.6 ± 1.9

13.1 ± 1.7

0.98

Valerate (C5)

2.3 ± 0.3

2.0 ± 0.3

2.2 ± 0.2

2.2 ± 0.2

0.66

Sum SCFA1

Gut microbiota groups (%)

70.8 ± 5.3

69.5 ± 7.8

71.6 ± 6.7

73.1 ± 6.5

0.90

Bac303

7.1 ± 1.8

5.4 ± 1.4

5.5 ± 1.9

9.4 ± 3.0

0.72

Erec482

26.1 ± 2.7

24.3 ± 3.4

23.2 ± 2.9

23.0 ± 2.7

0.76

Rrec584

10.0 ± 2.2

10.6 ± 2.4

8.6 ± 1.8

6.9 ± 1.4

0.78

Clep866

11.4 ± 1.2

13.6 ± 1.7

14.1 ± 2.0

10.7 ± 1.7

0.66

Ato291

2.4 ± 0.6

2.8 ± 1.0

3.5 ± 0.7

3.8 ± 0.7

0.25

Bif164

4.0 ± 1.0

2.2 ± 0.8

2.7 ± 0.7

2.7 ± 1.0

0.46

Prop853

4.9 ± 1.2

7.9 ± 1.3

9.5 ± 1.8

6.7 ± 1.6

0.13

Fecal dry mass (%)

26.0 ± 1.8

28.2 ± 2.7

26.3 ± 1.8

26.4 ± 1.8

0.98

  1. All values are mean ± SEM. HCF, diet high in cereal fiber; HP, diet high in protein; MIX, diet moderately high in both cereal and protein. M value, insulin mediated glucose uptake as a measurement for whole body insulin sensitivity. SCFA, fecal short chain fatty acids.
  2. Bac303, Bacteroides-Prevotella; Erec482, Clostridium coccoides - Eubacterium rectale cluster; Rrec584, Roseburia genus, Clep866, Clostridium leptum cluster; Ato291, Atopobium cluster; Bif164, Bifidobacterium group; Prop853, clostridial cluster IX. Total bacteria were detected with the EUB338 probe.
  3. 1 P values refer to the respective treatment × time interaction in the full model
  4. 2Sum SCFA includes the measurement of fecal iso-acids