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Table 3 Markers of colonic fermentation, according to diet, after 6 and 18 weeks.

From: Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity

   6 weeks    18 weeks  
  control HCF HP MIX p value control HCF HP MIX p value 1
Fecal SCFA (mM)           
Acetate (C2) 34.4 ± 3.3 42.2 ± 6.1 37.4 ± 2.8 41.7 ± 5.4 0.75 37.2 ± 2.6 44.1 ± 5.7 40.4 ± 3.9 39.8 ± 5.3 0.79
Propionate (C3) 12.8 ± 1.8 13.1 ± 1.7 15.0 ± 1.6 15.4 ± 1.6 0.28 14.1 ± 1.4 16.5 ± 2.2 17.4 ± 2.3 13.7 ± 1.2 0.77
Butyrate (C4) 11.3 ± 2.1 15.1 ± 2.8 15.6 ± 1.7 14.8 ± 2.7 0.41 13.3 ± 1.8 13.8 ± 2.0 12.9 ± 1.4 12.4 ± 1.7 0.98
Valerate (C5) 2.2 ± 0.3 1.9 ± 0.3 3.1 ± 0.3 2.4 ± 0.3 0.037 2.9 ± 0.3 2.4 ± 0.3 3.1 ± 0.4 2.6 ± 0.3 0.48
Sum SCFA2 63.7 ± 6.4 74.8 ± 9.5 75.6 ± 5.9 77.6 ± 9.0 0.42 71.6 ± 5.6 80.4 ± 9.7 78.2 ± 7.2 72.1 ± 7.3 0.90
Fecal dry mass (FDM, %)
FDM (%) 25.4 ± 2.1 34.3 ± 2.7 28.2 ± 1.9 28.3 ± 1.8 0.08 27.8 ± 1.4 30.4 ± 2.7 27.0 ± 1.7 30.1 ± 2.3 0.35
  1. All values are mean ± SEM. Baseline values are shown in Table 1. HCF, diet high in cereal fiber; HP, diet high in protein; MIX, diet moderately high in both cereal and protein. 1P values refer to the respective treatment × time interaction in the full model. 2Sum SCFA includes the measurement of fecal iso-acids