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Table 3 Markers of colonic fermentation, according to diet, after 6 and 18 weeks.

From: Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity

  

6 weeks

  

18 weeks

 
 

control

HCF

HP

MIX

p value

control

HCF

HP

MIX

p value 1

Fecal SCFA (mM)

          

Acetate (C2)

34.4 ± 3.3

42.2 ± 6.1

37.4 ± 2.8

41.7 ± 5.4

0.75

37.2 ± 2.6

44.1 ± 5.7

40.4 ± 3.9

39.8 ± 5.3

0.79

Propionate (C3)

12.8 ± 1.8

13.1 ± 1.7

15.0 ± 1.6

15.4 ± 1.6

0.28

14.1 ± 1.4

16.5 ± 2.2

17.4 ± 2.3

13.7 ± 1.2

0.77

Butyrate (C4)

11.3 ± 2.1

15.1 ± 2.8

15.6 ± 1.7

14.8 ± 2.7

0.41

13.3 ± 1.8

13.8 ± 2.0

12.9 ± 1.4

12.4 ± 1.7

0.98

Valerate (C5)

2.2 ± 0.3

1.9 ± 0.3

3.1 ± 0.3

2.4 ± 0.3

0.037

2.9 ± 0.3

2.4 ± 0.3

3.1 ± 0.4

2.6 ± 0.3

0.48

Sum SCFA2

63.7 ± 6.4

74.8 ± 9.5

75.6 ± 5.9

77.6 ± 9.0

0.42

71.6 ± 5.6

80.4 ± 9.7

78.2 ± 7.2

72.1 ± 7.3

0.90

Fecal dry mass (FDM, %)

FDM (%)

25.4 ± 2.1

34.3 ± 2.7

28.2 ± 1.9

28.3 ± 1.8

0.08

27.8 ± 1.4

30.4 ± 2.7

27.0 ± 1.7

30.1 ± 2.3

0.35

  1. All values are mean ± SEM. Baseline values are shown in Table 1. HCF, diet high in cereal fiber; HP, diet high in protein; MIX, diet moderately high in both cereal and protein. 1P values refer to the respective treatment × time interaction in the full model. 2Sum SCFA includes the measurement of fecal iso-acids