Figure 3
Group mean glycolytic metabolism ±SD. A- Extracellular acidification rate (ECAR) of rhabdomyosarcoma cells treated with either ethanol control (final concentration = 0.1%) or OEP or CHD at 90 μg/ml (High) for 24 hours. B- Baseline ECAR following treatment described above. C- Peak ECAR following addition of oligomycin, an inhibitor of oxidative phosphorylation. D- Peak ECAR during peak oxygen consumption rate (OCR) following addition of carbonyl cyanide p-[trifluoromethoxy]-phenyl-hydrazone (FCCP), a mitochondrial uncoupling agent, in addition to previously added oligomycin. NOTES: * indicates p < 0.05, ** indicates p < 0.01, and *** indicates p < 0.001 compared with control.