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Table 2 Lipid profiles, liver function, and levels of glucose and insulin in serum

From: Anti-diabetic effect of sorghum extract on hepatic gluconeogenesis of streptozotocin-induced diabetic rats

 

NC

DM

DM-SE 0.4

DM-SE 0.6

DM-G

Triglycerides (mmol/L)

0.92±0.15a

1.86±0.13b

0.75±0.13a

0.68±0.12a

0.89±0.02a

Total cholesterol (mmol/L)

2.01±0.10a

2.70±0.19b

1.81±0.05a

1.81±0.06a

2.14±0.10a

HDL-cholesterol (mmol/L)

1.20±0.04a

1.33±0.02a

1.28±0.02a

1.34±0.06a

1.02±0.09b

LDL-cholesterol (mmol/L)

0.73±0.03a

1.25±0.07b

0.82±0.07a

0.72±0.04a

0.88±0.05a

Glutamic oxaloacetic transaminase (IU/L)

42.81±1.19

46.02±2.92

42.94±2.05

44.26±0.73

45.03±1.52

Glutamic pyruvic transaminase (IU/L)

14.54±3.45

12.72±1.20

13.78±1.94

10.17±0.73

9.68±1.96

Glucose (mmol/L)

1.18±0.06a

1.67±0.12c

1.51±0.07bc

1.29±0.02b

1.21±0.12a

Insulin (pmol/L)

3.73±0.27a

1.25±0.20b

1.64±0.26ab

1.91±0.11ab

3.69±1.46a

AUC of glucose (mmol·min/L)

748.25±27.39a

1250.25±35.24c

881.20±39.61b

907.76±29.55b

781.39±23.36a

  1. Values are expressed as mean ± SEM (n = 5); NC, normal control rats administrated saline; DM, rats with diabetes mellitus administrated saline; DM-SE 0.4, rats with diabetes mellitus administrated 0.4 g/kg body weight of sorghum extract; DM-SE 0.6, rats with diabetes mellitus administrated 0.6 g/kg body weight of sorghum extract; DM-G, rats with diabetes mellitus administrated 0.7 mg/kg body weight of glibenclamide; AUC, area under the curve during intraperitoneal glucose tolerance tests. The values in the rows with different letters were significantly different at p < 0.05 using ANOVA with Duncan’s multiple range test.