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Table 2 Lipid profiles, liver function, and levels of glucose and insulin in serum

From: Anti-diabetic effect of sorghum extract on hepatic gluconeogenesis of streptozotocin-induced diabetic rats

  NC DM DM-SE 0.4 DM-SE 0.6 DM-G
Triglycerides (mmol/L) 0.92±0.15a 1.86±0.13b 0.75±0.13a 0.68±0.12a 0.89±0.02a
Total cholesterol (mmol/L) 2.01±0.10a 2.70±0.19b 1.81±0.05a 1.81±0.06a 2.14±0.10a
HDL-cholesterol (mmol/L) 1.20±0.04a 1.33±0.02a 1.28±0.02a 1.34±0.06a 1.02±0.09b
LDL-cholesterol (mmol/L) 0.73±0.03a 1.25±0.07b 0.82±0.07a 0.72±0.04a 0.88±0.05a
Glutamic oxaloacetic transaminase (IU/L) 42.81±1.19 46.02±2.92 42.94±2.05 44.26±0.73 45.03±1.52
Glutamic pyruvic transaminase (IU/L) 14.54±3.45 12.72±1.20 13.78±1.94 10.17±0.73 9.68±1.96
Glucose (mmol/L) 1.18±0.06a 1.67±0.12c 1.51±0.07bc 1.29±0.02b 1.21±0.12a
Insulin (pmol/L) 3.73±0.27a 1.25±0.20b 1.64±0.26ab 1.91±0.11ab 3.69±1.46a
AUC of glucose (mmol·min/L) 748.25±27.39a 1250.25±35.24c 881.20±39.61b 907.76±29.55b 781.39±23.36a
  1. Values are expressed as mean ± SEM (n = 5); NC, normal control rats administrated saline; DM, rats with diabetes mellitus administrated saline; DM-SE 0.4, rats with diabetes mellitus administrated 0.4 g/kg body weight of sorghum extract; DM-SE 0.6, rats with diabetes mellitus administrated 0.6 g/kg body weight of sorghum extract; DM-G, rats with diabetes mellitus administrated 0.7 mg/kg body weight of glibenclamide; AUC, area under the curve during intraperitoneal glucose tolerance tests. The values in the rows with different letters were significantly different at p < 0.05 using ANOVA with Duncan’s multiple range test.