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Figure 2 | Nutrition & Metabolism

Figure 2

From: Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in db/db mice

Figure 2

Changes in insulin resistance after 10 weeks of treatment with EGCG or rosiglitazone. Peripheral insulin sensitivity was assessed in control db/db mice and db/db mice receiving a diet supplemented with 1% (w/w) EGCG or 0.0021% (w/w) rosiglitazone (Rosi) for 10 weeks. Insulin resistance was evaluated by two different means: Shown in A is homeostasis model assessment-estimated insulin resistance (HOMA-IR) that was calculated as fasting glucose (mM) * fasting insulin (μU/ml)/22.5. Quantitative Insulin Sensitivity check (QUICKI) is shown in B and was calculated as 1/[log ((fasting glucose (mg/dl) + (fasting insulin (μU/ml))]. Bars represent mean ± SEM for 9 mice in each group. * denotes P < 0.05 for a chance difference vs controls using one-way ANOVA in conjunction with Dunnett's multiple comparison test.

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