Figure 3

Effects of 10 weeks of treatment with EGCG or rosiglitazone on pancreatic islet morphology and β cell area. Light microscopic appearance and histomorphometric analysis of pancreatic islet morphology and β-cell area in control db/db mice and db/db mice receiving dietary supplementation with 1% (w/w) EGCG or 0.0021% (w/w) rosiglitazone (Rosi) for 10 weeks. H&E staining was used and original magnification was 200 x. Bars represent mean ± SEM for 9 mice in each group. * denotes P < 0.001 (number of pathological islets) and P < 0.01 (β cell area) for chance differences vs controls using one-way ANOVA in conjunction with Dunnett's multiple comparison test.