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Table 5 The modulation of islet morphometry

From: Jerusalem artichoke and chungkookjang additively improve insulin secretion and sensitivity in diabetic rats

  Diabetic-CON (n=7) CKJ (n=7) HTL (n=7) CKJ+HTL (n=7) Normal-CON (n=7)
β-cell area (%) 6.4±0.7b 7.0±0.7ab 6.6±0.7b 7.8±0.8a 5.6±0.7c*
Individual β-cell size (μm2) 242.4±31.1a 221.3±25.4ab 215.6±24.7b 190.5±25.4b 182.2±26.8b*
Absolute β-cell mass (mg) 21.1±2.6c 23.4±2.7bc 22.8±2.5c 26.3±2.8b 34.6±4.8a*
BrdU+ cells (% BrdU+ cells of islets) 0.83±0.10c 0.95±0.11b 0.86±0.12bc 1.15±0.13a 0.74±0.09c*
Apoptosis (% apoptotic bodies of islets) 0.73±0.08a 0.68±0.08ab 0.65±0.08b 0.60±0.07b 0.65±0.10b*
Ratio of β:α cells 4.6±0.5b 5.8±0.6b 5.6±0.6b 6.3±0.7a 6.0±0.8a*
  1. Values are mean±SD. Rats in the normal-control (Normal-CON) and diabetic-control (Diabetic-CON) was fed high fat diets while diabetic rats in the CKJ, HTL, and CKJ+HTL groups were provided with high fat diets supplemented with 5% CKJ, 5% HTL, and 5% CKJ+ 5% HTL, respectively.
  2. *Significantly different among the groups at p<0.05 by one-way ANOVA.
  3. a,b,cValues in the same row with different superscripts were significantly different in Tukey test at P<0.05.