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Table 2 Bone characteristics of OVX rats fed with low or high vitamin K for 6 wk1

From: Vitamin K supplementation does not prevent bone loss in ovariectomized Norway rats

  Control2 PK:0.14 mg/kg diet BP2 PK:0.14 mg/kg diet PK 107 mg/kg diet MK-4 147 mg/kg diet MK-7 201 mg/kg diet
Body weight, g 329.6 ± 3.6 317.2 ± 4.2 331.9 ± 3.8 330.2 ± 3.9 338.3 ± 4.9
Ultimate Force, N 231.8 ± 17.0a 433.3 ± 21.0c 295.0 ± 15.0ab 245.8 ± 18.8ab 248.4 ± 16.2ab
Stiffness, Nmm 163.9 ± 20.1a 258.8 ± 30.2b 172.8 ± 17.1a 156.1 ± 19.4a 128.9 ± 10.9a
Femur Ca, mg/g 133.3 ± 1.8a 152.2 ± 2.2c 135.2 ± 3.1a 125.7 ± 2.4b 128.0 ± 1.4ab
Serum Ca, mg/L 114.3 ± 0.8a 108.1 ± 0.7b 112.3 ± 1.0a 113.8 ± 0.6a 113.0 ± 0.8a
Serum PO4, mg/L 90.9 ± 2.2a 75.8 ± 1.3b 87.2 ± 2.4a 86.9 ± 1.9a 88.2 ± 2.4a
  1. 1 Values are means ± SED, n = 16. 2 Low vitamin K diet (Harlan Teklad, TD. 97053). a,b,c When comparing measures across the five groups, means with different letter subscripts are statistically different, P < 0.05