Serum IFN-γ, IL-10 and IL-5 concentration (pg/ml) changes from Pre. Serum IFN-γ (A) and IL-10 (B) concentration changes were not significantly different within or between groups. However, IL-5 (C) displayed a significant (P < 0.05) treatment, time interaction. Although no significant differences were observed within the 4000 IU group, there was a significant and transient decrease in IL-5 at 14-d (1P < 0.05 vs. 7-d) in the placebo and increase at 28-d (2P < 0.05 vs. 7-d and 14-d) in 200 IU group. At 28-d, IL-5 changes were also significantly (*P < 0.05) different between the placebo and 200 IU groups. Figure legend provided in 'A'. Data presented as mean (SD).