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Table 4 Associations of 25-hydroxyvitamin D3 and parathyroid hormone with blood pressure in antihypertensive medication users and non-users a)

From: Serum 25-hydroxyvitamin D3, parathyroid hormone and blood pressure in an elderly cohort from Germany: a cross-sectional study

Women (n= 90)   BP medication users (n= 55) BP medication non-users (n= 35)
   SBP (mmHg) DBP (mmHg) SBP (mmHg) DBP (mmHg)
25(OH)D3 (nmol/L) Model 1 -0.119 -0.122 -0.069 0.201
  Model 2 -0.085 -0.146 0.077 0.133
  Model 3 -0.103 -0.164 0.197 0.158
iPTH (pmol/L) Model 1 -0.062 -0.088 0.202 -0.004
  Model 2 -0.077 -0.066 0.132 -0.022
  Model 3 -0.096 -0.097 0.215 0.045
Men ( n = 42)   BP medication users ( n = 24) BP medication non-users ( n = 18)
   SBP (mmHg) DBP (mmHg) SBP (mmHg) DBP (mmHg)
25(OH)D3 (nmol/L) Model 1 -0.163 -0.015 -0.674 ** -0.579 *
  Model 2 -0.207 -0.088 -0.619 * -0.529 *
  Model 3 -0.207 -0.088 -0.843 ** -0.785 **
iPTH (pmol/L) Model 1 0.127 0.185 0.010 -0.194
  Model 2 -0.015 0.054 -0.053 -0.144
  Model 3 -0.016 0.053 -0.449 -0.512 *
  1. Abbreviations: BP medication, antihypertensive medication; SBP, systolic blood pressure; DBP, diastolic blood pressure; 25(OH)D3, 25-hydroxyvitamin D3; iPTH, intact parathyroid hormone.
  2. a) Multiple linear regression analyses with SBP and DBP as dependent variables and 25(OH)D3 and iPTH as independent variables after splitting the cohort into antihypertensive medication users and non-users, respectively. The results are expressed in terms of the standardised coefficient β. Model 1: unadjusted association. Model 2: model 1 additionally adjusted for waist-to-hip ratio and calcium intake (mg/d) in men and age (y) and total body fat (%) in women. Model 3: model 2 plus mutual adjustment for iPTH (pmol/L) and 25(OH)D3 (nmol/L) in both the male and female model, respectively. * P < 0.05; ** P < 0.01.