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Table 2 Effect of HF diet and Kupffer cells reduction on triacylglycerol content in the liver

From: Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages

  

SD

SD + GdCl3

P

HF

HF + GdCl3

P

TAG (μmol/g)

fasted

7.1 ± 0.2

8.1 ± 0.4

N.S.

21.4 ± 1.4x

14.1 ± 1.7y

0.05

 

fed

4.4 ± 0.4

5.3 ± 0.4

N.S.

25.2 ± 0.7x

16.4 ± 0.3y

0.01

DAG (nmol/g)

fasted

10.8 ± 0.3

12.4 ± 0.6

N.S.

31.2 ± 1.1x

54.6 ± 2.5y

0.01

 

fed

7.3 ± 0.2

6.8 ± 0.2

N.S.

36.7 ± 1.8x

69.3 ± 2.1y

0.001

  1. P value indicates the significance of GdCl3 treatment within each group; x p < 0.05 HF vs SD; y p < 0.05 HF + GdCl3 vs SD + GdCl3. Data are given as mean ± S.E.M., n = 6.