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Table 3 Effect of HF diet and Kupffer cells reduction on glycogen content in the liver

From: Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages

   SD SD + GdCl3 P HF HF + GdCl3 P
glycogen (μmol/g) starved 12 ± 2.6 65 ± 8.5 0.01 17 ± 1.6 49 ± 8 0.05
  fed + ins 226 ± 13 196 ± 13 N.S. 198 ± 19 110 ± 18 0.01
  1. Animals in "fed + ins" group were provided food ad libitum and 30 min prior decapitation were administered insulin (6 U/kg b.wt.) i.p. The glycogen is expressed in glucose equivalents (μmoles per g wet weight) P value indicates the significance of GdCl3 treatment within each group; y p < 0.05 HF + GdCl3 vs SD + GdCl3. Data are given as mean ± S.E.M., n = 6.