Effects of synthetic inulin and fluvastatin on body and tissue weights, portal glucose levels, and hepatic lipid profiles in rats fed a standard (SD), inulin-supplemented standard (SD + I), high-fat and high-sucrose (HF), or inulin-supplemented high-fat and high-sucrose (HF + I) diet. Rats (7 weeks of age) were fed the SD, SD + I, HF, or HF + I diet for 1 week, and then administered fluvastatin (0, 4, or 8 mg/kg) with the diet daily. The rats were sacrificed 14 days after starting the administration of fluvastatin. Values are the mean ± S.E. of 4 determinations. *p < 0.05, **p < 0.01, ***p < 0.001 versus SD diet-fed control rats; # p < 0.05, ##p < 0.01, ###p < 0.001 versus HF diet-fed control rats. C, vehicle; F, fluvastatin; 4, 4 mg/kg; 8, 8 mg/kg.