Effects of synthetic inulin and fluvastatin on hepatic ethoxyresolufin O -deethylase (A) and methoxyresolufin O -deethylase (B) activities in SD or HF diet-fed rats. Rats (7 weeks of age) were fed the SD, SD + I, HF, or HF + I diet for 1 week, and then administered fluvastatin (0 or 4 mg/kg) with the diet daily. The rats were sacrificed 14 days after starting the administration of fluvastatin. The microsome proteins were prepared and analyzed for ethoxyresolufin O-deethylase and methoxyresolufin O-denethylase activities. Values are the mean ± S.E. of 3 determinations. *p < 0.05, **p < 0.01, ***p < 0.001 versus SD diet-fed control rats; #p < 0.05, ##p < 0.01 versus HF-fed control rats.