Figure 5From: Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recoveringHigh glycemic food intake could cause inflammation and diseases as a result of hyperinsulinemia. The pathways in the shaded area have been extensively described by Cordain [64] (part B). Part A: The consequential reactive hyperglycemia is another deleterious pathway. Hyperglycemia is a danger signal, which activates the systemic stress system. Chronic activation will suppress the IIS, resulting in low grade inflammation and an increased vulnerability for excessive inflammation.Back to article page