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Table 6 Volumetric bone mineral density, morphometric and mechanical parameters of femur in pigs at slaughter age from the Control group and the groups being under prenatal influence of alpha-ketoglutarate (AKG Group), β -hydroxy- β -methylbutyrate (HMB Group) or alpha-ketoglutarate and β -hydroxy- β -methylbutyrate (AH Group)

From: Effects of combined maternal administration with alpha-ketoglutarate (AKG) and β-hydroxy-β-methylbutyrate (HMB) on prenatal programming of skeletal properties in the offspring

Investigated parameter

Control Group

AKG Group

HMB Group

AH Group

(n = 65)

(n = 63)

(n = 65)

(n = 66)

Bone weight (g)

300.1 a

319.3 b

324.8 bc

333.7 c

± 4.1

± 3.5

± 3.5

± 4.0

Bone length (mm)

197.4 a

197.7 a

196.9 a

201.0 b

± 1.0

± 1.1

± 1.0

± 0.8

Trabecular bone mineral density (g/cm3)

1.360 a

1.414 b

1.454 c

1.410 b

± 0.005

± 0.006

± 0.007

± 0.005

Cortical bone mineral density (g/cm3)

2.387 a

2.565 b

2.603 c

2.560 b

± 0.020

± 0.010

± 0.008

± 0.009

Cross-sectional area (mm2)

288.3 a

312.9 b

319.5 b

320.8 b

± 6.8

± 3.9

± 4.9

± 4.7

Second moment of inertia (mm4)

17 536 a

19 065 ab

19 851 bc

21 396 c

± 716

± 492

± 584

± 644

Mean relative wall thickness

0.601 a

0.668 b

0.703 b

0.620 a

± 0.014

± 0.012

± 0.017

± 0.012

Cortical index

37.16 a

39.70 b

40.78 b

37.95 a

± 0.536

± 0.433

± 0.578

± 0.467

Maximum elastic strength (N)

4066 a

4854 bc

5184 c

4644 b

± 172

± 139

± 170

± 129

Ultimate strength (N)

5377 a

5964 b

6288 b

6229 b

± 168

± 130

± 153

± 169

  1. Values are means ± SEM.
  2. abcMean values that do not share common superscript letter in the same row differ significantly for P < 0.05 as compared by multiple range Duncan’s test.