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Table 1 The characteristics of 568 CHD patients who were stratified according to serum TSH concentration

From: Thyroid stimulating hormone, independent of thyroid hormone, can elevate the serum total cholesterol level in patients with coronary heart disease: a cross-sectional design

 

Serum TSH concentration (mIU/L)

P value

Total

<0.27

0.27-1.57

1.58-2.88

2.89-4.19

≥4.2

Age (y)

64.84(11.64)

65.47(11.27)

61.92(11.54)

63.69(10.57)

64.46(10.82)

0.052

63.76(11.28)

SBP (mm Hg)

137.47(17.01)

134.77(22.72)

132.87(19.45)

136.51(21.17)

136.94(20.35)

0.481

134.74(20.79)

DBP (mm Hg)

80.42(7.77)

79.02(12.54)

79.22(11.96)

78.51(11.83)

80.43(10.54)

0.847

79.27(11.78)

FPG (mmol/L)

6.1328(1.24)

5.4976(1.04)

5.3802(1.30)

5.0863(0.55)

5.2059(0.83)

0.001

5.3733(1.093)

TC (mmol/L)

4.6163 (1.3305)

4.8699(1.03)

4.9598(1.15)

4.9685(1.03)

5.3518(1.34)

0.013

4.9829(1.15)

TG (mmol/L)

1.3226(0.69)

1.3669(0.82)

1.7644(1.62)

1.6951(0.85)

1.9766(1.66)

0.003

1.6538(1.32)

LDL (mmol/L)

3.00(0.851)

2.91(0.77)

2.88(0.841)

2.91 (0.74)

3.16 (0.91)

0.111

2.94(0.82)

HDL (mmol/L)

1.1506(0.29)

1.2891(0.35)

1.3229(0.37)

1.2762(0.32)

1.3557(0.29)

0.141

1.3060(0.34)

UA (μmol/L)

297.9688 (107.94)

313.9742(90.85)

321.0955(101.73)

311.7162(70.90)

321.63(109.47)

0.817

317.0161(95.98)

TSH (mIU/L)

0.1498(0.11)

1.0532(0.34)

2.1371(0.35)

3.5424(0.56)

19.760(33.33)

0.000

4.6504(14.52)

FT3 (pmol/L)

8.1885(6.20)

4.5007(0.79)

4.5055(0.71)

4.5020(0.83)

3.5891(1.24)

0.000

4.4864(1.58)

FT4 (pmol/L)

31.2682(17.85)

17.5750(2.50)

17.3971(2.84)

16.7438(2.44)

13.4475(4.76)

0.000

17.2147(5.30)

Smoking status

A

17

121

159

72

80

0.0000

 

B

0

23

26

3

5

0.0008

 

C

2

23

21

6

1

0.0009

 
 

D

0

2

5

1

1

0.2222

 
  1. 1. The data are presented as the mean ± standard deviation (SD). The SD is shown in parentheses.
  2. 2. The groups were compared using a Chi-squared test. P-values less than 0.05 were considered statistically significant. 3. Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, free plasma glucose; TC, total cholesterol; TG, triglycerides; LDL, low-density lipoprotein cholesterol; HDL, high-density lipoprotein cholesterol; and UA, uric acid. 4. The following reference ranges were based on our laboratory standards: Plasma glucose (3.9-6.1 mmol/L), total cholesterol (3.6-6.2 mmol/L), triglycerides (<1.71 mmol/L), low-density lipoprotein cholesterol (0–3.36 mmol/L), high-density lipoprotein cholesterol (>1.15 mmol/L), TSH (0.27–4.2 mIU/L), FT3 (3.1-6.8 pmol/L), FT4 (12–22 pmol/L) and uric acid (142–339 μmol/L). 4. The smoking status categories are as follows: A, B, C and D represent no smoking, smoking 1–339, 440–1099, and above 1100 cigarettes per year, respectively. The data are presented as the number of people in each category.