Table 4 Ratios of differentially expressed genes related to oxidative processes

Gluthatione metabolism

Glutathione peroxidase 1

GPX1

2876

NM_000581.2

-

-

-

-

-

−2.48 ³

NM_201397.1

Glutathione S-transferase Mu 3

GSTM3

2947

NM_000849.4

−2.30 ¹

4.12 ²

2.47 ²

-

-

-

Glutathione synthetase

GSS

2937

NM_000178.2

−7.97 ¹

-

-

-

-

-

Phospholipid hydroperoxide glutathione peroxidase, mitochondrial

GPX4

2879

NM_001039848.1

-

−3.74 ¹

-

-

-

-

NM_001039847.1

NM_002085.3

Glutathione S-transferase P

GSTP1

2950

NM_000852.3

-

−2.00 ²

-

-

-

-

Gamma-glutamyltransferase 5

GGTLA1

2687

NM_001099782.1

3.44 ¹

14.90 ¹

7.98 ¹

-

-

-

NM_001099781.1

NM_004121.2

Glutathione peroxidase 3 (plasma)

GPX3

2878

NM_002084.3

-

-

−2.15 ¹

-

-

-

Glutathione reductase

GSR

2936

NM_000637.2

-

-

2.38 ³

-

-

-

Matrix metalloproteinases

Matrix metalloproteinase-25

MMP25

64386

NM_022468.4

-

-

-

2.14 ²

-

−2.30 ¹

Metalloproteinase inhibitor 2

TIMP2

7077

NM_003255.4

-

−4.18 ¹

−2.29 ¹

-

-

-

stromelysin-1

MMP3

4314

NM_002422.3

-

-

−2.17 ¹

-

-

-

72 kDa type IV collagenase

MMP2

4313

NM_001127891.1

-

−3.91 ¹

−6.16 ¹

-

-

-

NM_004530.4

Cytochrom P450 enzymes

Cytochrome P450 1A2

CYP1A2

1544

NM_000761.3

-

-

-

-

-

−7.74 ²

Cytochrome P450 2A7

CYP2A7

1548

NM_000762.5

-

−2.46 ¹

-

−2.42 ¹

−2.70 ¹

Cytochrome P450 4X1

CYP4X1

260293

NM_178033.1

-

−5.66 ¹

−11.35 ¹

-

-

-

Cytochrome P450 26A1

CYP26A1

1592

NM_057157.2

2.87 ¹

-

-

-

-

-

NM_000783.3

Cytochrome P450 2B6

CYP2B6

1555

NM_000767.4

2.60 ¹

-

-

-

-

-

Cytochrome P450 4F12

CYP4F12

66002

NM_023944.3

2.46 ¹

-

-

-

-

-

Cholesterol side-chain cleavage enzyme, mitochondrial

CYP11A1

1583

NM_001099773.1

−2.30 ¹

−2.78 ¹

−2.79 ¹

-

-

-

NM_000781.2

Cytochrome P450 26B1

CYP26B1

56603

NM_019885.2

−3.11 ¹

-

-

-

-

-

Cytochrome P450 2C19

CYP2C19

1557

NM_000769.1

−7.48 ¹

-

-

-

-

-

Steroid 17-alpha-hydroxylase/ 17,20 lyase

CYP17A1

1586

NM_000102.3

−7.96 ¹

-

−4.19 ¹

-

-

-

Cytochrome P450 2J2

CYP2J2

1573

NM_000775.2

-

-3.54 ¹

-

-

-

-

Cytochrome P450 27C1

CYP27C1

339761

NM_001001665.3

-

−4.46 ¹

−3.41 ¹

-

-

-

Cytochrome P450 2A13

CYP2A13

1553

NM_000766.3

-

−4.49 ¹

−8.90 ¹

Others

Extracellular superoxide dismutase [Cu-Zn]

SOD3

6649

NM_003102.2

-

-

4.70 ³

-

-

2.91 ³

Catalase

CAT

847

NM_001752.2

-

13.15 ¹

8.90 ¹

-

-

-

Heme oxygenase 1

HMOX1

3162

NM_002133.1

-

−8.57 ¹

−17.52 ¹

-

-

-

Heme oxygenase 2

HMOX2

3163

NM_001127204.1

-

−11.44 ¹

7.84 ¹

-

-

-

NM_001127205.1

NM_001127206.1

NM_002134.3

Epoxide hydrolase 1

EPHX1

2052

NM_000120.3

-

-

3.14 ²

−2.24 ²

-

2.22 ²

NM_001136018.2

Arachidonate 5-lipoxygenase- activating protein

ALOX5AP

241

NM_001629.2

-

-

6.97 ¹

-

-

-

Nitric oxide synthase, endothelial

NOS3

4846

NM_000603.4

-

−4.22 ¹

−2.55 ¹

-

-

-

Nitric oxide synthase, inducible

NOS2

4843

NM_000625.4

-

−8.11 ¹

−4.77 ¹

-

-

-

Nitric oxide synthase-interacting protein

NOSIP

51070

NM_015953.3

-

-

-

-

-

3.64 ¹

NADPH oxidase 1

NOX1

27035

NM_013955.2

-

-

2.06 ¹

-

-

-

NM_007052.4