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Table 2 Effect of aspartame (ASP) and MSG on body weight, fat deposition and lipid profile

From: Interactive effects of neonatal exposure to monosodium glutamate and aspartame on glucose homeostasis

CONTROL   MSG   ASP   MSG + ASP   P-value Diet, Gender
6 Week Body Weight (g)         
male 18.1 ± 0.26  a  17.41 ± 0.33  a  17.97 ± 0.22  a  19.39 ± 0.19  b  <.0001
female 14.34** ± 0.17 14.15** ± 0.21 14.40** ± 0.15 15.95** ± 0.19 <.0001
17 Week Body Weight (g)         
male 24.92 ± 0.34  a  25.61 ± 0.32  a  25.5 ± 0.31  a  27.84 ± 0.42  b  <.0001
female 19.24** ± 0.19 18.70** ± 0.19 19.66** ± 0.26 21.61** ± 0.23 <.0001
Weight Change (%)         
male 37.79 ± 1.18a   46.46 ± 2.28b   42.03 ± 1.38ab   43.7 ± 2.04ab   0.06
female 34.41 ± 1.47 33.64** ± 1.28 36.67* ± 1.7 35.56** ± 1.12 <.0001
Visceral Fat (g)         
male 0.31 ± 0.02   0.34 ± 0.03   0.34 ± 0.03   0.38 ± 0.03   0.189
female 0.15** ± 0.02 0.14** ± 0.01 0.13** ± 0.01 0.18** ± 0.02 <.0001
Insulin (uIU/mL)         
male 8.76 ± 1.16   8.67 ± 1.7   5.43 ± 1.02   9.67 ± 1.83   0.197
female 4.61** ± 0.74 5.23 ± 0.65 4.34 ± 1.18 6.07 ± 1.20 <0.001
TG (mg/dL)         
male 124.56 ± 6.1a   92.88 ± 4.45b   95.97 ± 5.61b   125.39 ± 2.91a   <.0001
female 123.11 ± 5.05a 84.47 ± 4.56b 93.54 ± 5.59b 93.27** ± 5.03b <0.01
T-CHOL (mg/dL)         
male 133.33 ± 2.26  a  123.94 ± 1.19  b  118.17 ± 1.2  c  123.56 ± 1.01  b  <.0001
female 133 ± 1.81 123.56 ± 1.2 122.33** ± 0.81 124.5 ± 0.92 0.276
HDL-C (mg/dL)         
male 87.48 ± 5.24  a  71.19 ± 3.21  b  83.36 ± 2.39  ab  73.33 ± 2.52  b  <.01
female 57.62** ± 3.17   54.46** ± 2.19   51.16** ± 2.2   49.38** ± 1.7   <.0001
  1. Data presented are Means ± SEM (n = 18 per diet and per gender). P-values were calculated using 2-way ANOVA. Significant differences between diets are indicated using different letters in bold  abc . *,** indicates p-value of < .05 and < .01 for the comparison of males to females within each diet.
  2. Data presented are means ± SEM.
  3. P-values for diet and gender are calculated using two way ANOVA.
  4. Significant differences between diets are shown using different letters  abc .
  5. Diet*Gender interaction was found to be significant (P < 0.05). Letters abc indicate significant differences between diets separately for each gender.
  6. *,** indicate p-value of < .05, <.01 for the comparison of males to females within each diet.