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Table 1 Effects of theophylline (50 mg/kg bw) on body composition in rats bearing the Yoshida AH-130 ascites hepatoma

From: Theophylline is able to partially revert cachexia in tumour-bearing rats

   Experimental group    
  C(n = 6) T(n = 10) T + TPH(n = 7) ANOVA
     A B
Fat mass (g) 3.2 ± 1.1 −4.3 ± 0.5 −2.3 ± 0.7 0,000 0,045
Lean body mass (g) 23.5 ± 1.5 1.7 ± 1.7 7 ± 3 0,000 ns
Fluids (g) 0.03 ± 0.2 −0.7 ± 0.2 0.04 ± 0.3 0,034 0,025
  1. Results are expressed as the difference between day 0 (tumour inoculation) and day 7; mean ± SEM. C = non-tumour-bearing rats, T = tumour-bearing rats, T + TPH = tumour-bearing rats treated with theophylline. Statistical significance of the results by two-way analysis of variance (ANOVA); ns: non-significant differences. A (tumour effect); B (treatment effect).