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Table 2 Change in body weight gain, body composition and serum biochemistry of obesity-prone and obesity-resistant rats after 4 wk on a moderate fat diet

From: Dietary resistant starch dose-dependently reduces adiposity in obesity-prone and obesity-resistant male rats

 

Obesity resistant

Obesity prone

 

wk 01

wk 41

Δ (%)2

wk 01

wk 41

Δ (%)2

Body weight, g

297 ± 4

366 ± 5

26

322 ± 4

427 ± 5

33 **

Fat mass, %

5.8 ± 0.3

10.5 ± 0.5

4.7

7.0 ± 0.3

13.3 ± 0.6

6.3 *

Bone mineral density, g/cm3

0.183 ± 0.001

0.207 ± 0.001

13.6

0.185 ± 0.001

0.216 ± 0.0001

17.4 **

Fasting glucose, mmol/L

5.3 ± 0.1

6.3± 0.1

20

5.5 ± 0.1

6.4 ± 0.1

18

Fasting insulin3, pmol/L

94 ± 27

267 ± 48

210

141 ± 32

344 ± 56

250

HOMA-IR3

0.5 ± 0.1

1.8 ± 0.3

300

0.9 ± 0.2

2.5 ± 0.5

280

  1. 1n=48 obesity-resistant, n=48 obesity-prone.
  2. 2 Percent change from 0 to 4 wk. Significant difference between obesity-resistant and obesity-prone rats is denoted by * P < 0.05, ** P < 0.0001.
  3. 3 Fasting insulin and HOMA-IR were measured in a subset of rats; n=4 obesity resistant and n=3 obesity prone.