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Table 2 Change in body weight gain, body composition and serum biochemistry of obesity-prone and obesity-resistant rats after 4 wk on a moderate fat diet

From: Dietary resistant starch dose-dependently reduces adiposity in obesity-prone and obesity-resistant male rats

  Obesity resistant Obesity prone
  wk 01 wk 41 Δ (%)2 wk 01 wk 41 Δ (%)2
Body weight, g 297 ± 4 366 ± 5 26 322 ± 4 427 ± 5 33 **
Fat mass, % 5.8 ± 0.3 10.5 ± 0.5 4.7 7.0 ± 0.3 13.3 ± 0.6 6.3 *
Bone mineral density, g/cm3 0.183 ± 0.001 0.207 ± 0.001 13.6 0.185 ± 0.001 0.216 ± 0.0001 17.4 **
Fasting glucose, mmol/L 5.3 ± 0.1 6.3± 0.1 20 5.5 ± 0.1 6.4 ± 0.1 18
Fasting insulin3, pmol/L 94 ± 27 267 ± 48 210 141 ± 32 344 ± 56 250
HOMA-IR3 0.5 ± 0.1 1.8 ± 0.3 300 0.9 ± 0.2 2.5 ± 0.5 280
  1. 1n=48 obesity-resistant, n=48 obesity-prone.
  2. 2 Percent change from 0 to 4 wk. Significant difference between obesity-resistant and obesity-prone rats is denoted by * P < 0.05, ** P < 0.0001.
  3. 3 Fasting insulin and HOMA-IR were measured in a subset of rats; n=4 obesity resistant and n=3 obesity prone.