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Table 4 Large intestinal tissue weights and fermentation parameters of obesity-prone and obesity-resistant rats consuming diets with different levels of resistant starch for 4 wk 1

From: Dietary resistant starch dose-dependently reduces adiposity in obesity-prone and obesity-resistant male rats

 

Resistant starch, % of diet weight

Main Effects (P-value)

 

0%

4%

8%

12%

16%

RS

Phenotype

RS x Phenotype

Caecum

        

 Digesta weight, g

       

0.015

 Obesity-prone

1.7 ± 0.2 a

2.3 ± 0.3 a

6.4 ± 1.0 b

6.9 ± 1.0 b

11.5 ± 1.6 c

   

 Obesity-resistant

1.5 ± 0.1 a

2.5 ± 0.5 ab

6.0 ± 0.7 b

9.5 ± 0.9 c

7.4 ± 1.3 bc

   

 Total SCFA pool, mmol

169 ± 11 a

288 ± 43 ab

657 ± 83 bc

985 ± 150 c

1029 ± 150 c

0.0001

ns

ns

 Digesta pH

7.2 ± 0.1 c

6.8 ± 0.1 b

6.2 ± 0.1 a

6.0 ± 0.1 a

5.9 ± 0.1 a

0.0001

ns

ns

Colon

        

 Digesta weight, g

1.0 ± 0.1 a

1.9 ± 0.1 b

2.1 ± 0.2 bc

3.0 ± 0.2 d

3.2 ± 0.3 d

0.0001

ns

ns

 Total SCFA pool, mmol

69 ± 7 a

160 ± 14 b

184 ± 26 b

213 ± 20 b

215 ± 23 b

0.0001

0.0163

ns

 Digesta pH

7.3 ± 0.1 c

6.3 ± 0.1 b

6.0 ± 0.1 ab

6.0 ± 0.1 ab

5.8 ± 0.1 a

0.0001

ns

ns

Faeces

        

Faecal output g/d

1.7 ± 0.1 a

3.0 ± 0.2 ab

3.7 ± 0.3 b

5.8 ± 0.6 c

8.3 ± 0.5 d

0.0001

0.0284

ns

Faecal fat2, g/d

0.15 ± 0.02

0.09 ± 0.01

0.11 ± 0.02

0.09 ± 0.01

0.13 ± 0.01

ns

ns

ns

  1. 1 Values are means ± SEM. Labelled means without a common letter differ, P < 0.05. ns = not significant, P > 0.05. All dietary treatments consist of n=8 obesity-prone and n=12 obesity-resistant rats.
  2. 2n=8 (n=4 obesity-prone and n=4 obesity-resistant rats per group).
  3. 3 obesity-prone 188 ± 11 mmol, obesity-resistant 149 ± 11 mmol.
  4. 4 obesity-prone 4.9 ± 0.5 g/d, obesity-resistant 4.3 ± 0.2.