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Figure 5 | Nutrition & Metabolism

Figure 5

From: Comparisons of the iron deficient metabolic response in rats fed either an AIN-76 or AIN-93 based diet

Figure 5

Iron deficiency significantly affects the hepatic expression of mRNA involved in fat metabolism ( Fas , Acly , Scd1 ) and insulin signaling ( Pdk4 and Srebp1c ). The ID group also exhibited in significantly increased expression of Tfr1 and significantly decreased expression of the iron sensor hepcidin (Hamp1). mRNA levels were normalized to Cyclophilin B (Cyclo) mRNA as the invariant control. Numbers beneath gene names indicate CT value ± SEM obtained for the PF group. Cyclo Mean CT = 18.9 for both PF groups. Values are given as means ± SEM (n=8). *Indicates statistical difference between ID and PF animals within each diet group, p < 0.05.

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