Table 2 Fasting metabolites and postprandial measures according to the APOB insertion/deletion polymorphism in the study participants

Age (y)

52 ± 2

56 ± 1

53 ± 2

0.176

Gender (men/women)

36/16

53/17

23/2

0.090

Body mass index (kg/m²)

26.6 ± 0.4

27.2 ± 0.4

27.9 ± 0.8

0.184**

Fasting metabolites

Total cholesterol (mmol/l)

5.77 ± 0.12^A

6.26 ± 0.11^B

6.43 ± 0.21^B

0.004

Triacylglycerol (mmol/l)

1.62 ± 0.09^A

1.96 ± 0.10^B

2.25 ± 0.14^B

0.007

LDL-C (mmol/l)

3.75 ± 0.10^A

4.24 ± 0.11^B

4.32 ± 0.19^B

0.007

HDL-C (mmol/l)

1.29 ± 0.04^A

1.13 ± 0.03^B

1.04 ± 0.04^B

0.002

NEFA (μmol/l)

525.4 ± 31.5

503.5 ± 22.2

448.0 ± 22.1

0.079

Glucose (mmol/l)

5.23 ± 0.08

5.28 ± 0.07

5.39 ± 0.15

0.798

Insulin^∞ (pmol/l)

43.9 ± 3.37^A

48.9 ± 4.08^A

74.9 ± 12.3^B

0.007

HOMA-IR

1.73 ± 0.14^A

1.99 ± 0.18^A

3.15 ± 0.57^B

0.004

Postprandial summary measures

Triacylglycerol (mmol/l × 480 min)

AUC

1024.3 ± 52.5^A

1268.9 ± 61.3^B

1841.6 ± 135.4^C

<0.001

IAUC

273.3 ± 22.4^A

326.0 ± 25.4^A

511.6 ± 58.3^B

<0.001

NEFA (mmol/l × 300 min)^¥

AUC

160.0 ± 5.8

153.4 ± 6.2

149.8 ± 6.3

0.153

IAUC

94.8 ± 7.3

101.7 ± 3.9

91.3 ± 5.2

0.539

Glucose (mmol/l × 480 min)

AUC

2979.1 ± 48.9

2946.9 ± 83.9

3184.9 ± 62.4

0.527

IAUC

489.9 ± 43.9

557.7 ± 31.4

533.3 ± 34.7

0.306

Insulin^∞ (nmol/l × 480 min)

AUC

25.7 ± 8.6^A

24.8 ± 6.1^A

81.5 ± 23.0^B

0.036

IAUC

113.2 ± 21.5

91.2 ± 9.8

172.8 ± 25.4

0.108