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Figure 1 | Nutrition & Metabolism

Figure 1

From: Identification of residues/sequences in the human riboflavin transporter-2 that is important for function and cell biology

Figure 1

Predicted membrane topology of hRFVT-2 and location of predicted and clinically relevant mutations. A) hRFVT-2 is predicted to have 10 transmembrane domains with both N- and C-terminal tails oriented intracellularly [20,22]. Predicted and clinically relevant mutations are depicted in oval and rectangular shapes, respectively. B) Homology modelling of hRFVT-2 protein to show the location of predicted and clinically relevant mutations in the hRFVT-2 polypeptide. C) Comparison of amino acid sequences of human, mouse and rat RF transporters. The locations of the predicted amino acids are shown in box.

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