Effects of HC use on [DHA/EPA] desaturase indices in Caucasian females classified by genotype of rs174576 SNP. Results demonstrated that the significant effect of HC use is independent of genotype. Data presented as mean ± standard error mean. P-values were determined using multiple linear regression models which were adjusted for BMI, age, dietary LA, ALA, EPA and DHA, % total energy from dietary fat and physical activity. MM: major homozygous; Mm + mm: heterozygous + minor homozygous.