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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish

Fig. 5

E2f8 regulates fabp3 expression in zebrafish and human cells. (a) qPCR analysis of fabp3 in zebrafish analysed in Fig. 4. Fabp3 expression was suppressed by MO-e2f8 i.p. n = 5, *P < 0.05 vs. control MO (MO-con). (b-c) qPCR analysis of forced expression of E2F3 (b) and E2F8 (c) in HepG2 cells. n = 4, **P < 0.01 vs. control. (d-g) FABP family gene expression in E2F3-or E2F8-overexpressed (OE) cells. FABP3 were induced only in E2F8-OE cells (d), while FABP1 (e), FABP5 (f) and FABP7 (g) were not altered in these OE cell lines. n = 4, *P < 0.05 vs. control

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