Fig. 6

Anserine and creatine feeding to DIO-zebrafish. (a – b) Body weight and body length in the feeding experiment. Co-administration of anserine and creatine (AC) suppressed body weight increase (a), but not body length (b). n = 8, *P < 0.05 and **P < 0.01 vs. NF, and #P < 0.05 vs. HF. (c) Food intake during the feeding experiment. There is no difference between HF and HF + AC. n = 8. (d) For plasma TG, there is no difference between HF and HF + AC. n = 5-6, *P < 0.05 vs. NF. (e) AC decreased the level of fasting blood glucose. n = 4-6, *P < 0.05. (f) The area of lipid droplets of Oil Red O staining of liver. AC suppressed lipid accumulation in the liver of DIO-zebrafish. n = 7-8, **P < 0.01