Table 1 Altered metabolism of nitrate/nitrite in type 2 diabetic patients
From: Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications
Author | Study population | Findings |
|---|---|---|
Francesconi, 2001 [40] | Type 2 diabetic patients | Decreased urinary excretion of nitrate/nitrite after glycemic control; a positive correlation between fasting plasma glucose and urinary nitrate/nitrite |
Kawakatso, 2002 [35] | Type 2 diabetic patients with and without complications, compared with healthy controls | Lower nitrate/nitrite concentration in diabetic patients without complications; a higher nitrate/nitrite level in diabetic group with coronary artery disease |
Apakkan, 2003 [36] | Type 2 diabetic patients, compared with healthy controls | Higher serum and urine nitrate/nitrite in diabetic patients |
Zahedi, 2008 [37] | Subjects with type 2 diabetes and metabolic syndrome, compared with healthy controls | Higher serum nitrate/nitrite concentrations in subjects with type 2 diabetes and metabolic syndrome |
Shiekh, 2011 [34] | Type 2 diabetic patients, compared with healthy controls | Lower plasma levels of nitrate in diabetic patients |