Fig. 13

Effect of S. indicus extract on aortic lipid deposition in diet-induced hyperlipidemic LDL receptor-deficient mice. Mice were fed Western Diet for 4 weeks followed by treatment with S. indicus preparation by oral gavage for 8 weeks. Mice were fed WD during treatment period. At the end of 8 weeks of treatment, mice were bled retro-orbitally under isoflurane anesthesia, sacrificed by carbon dioxide asphyxiation, and aorta removed and processed for Oil Red O staining