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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Identification of a botanical inhibitor of intestinal diacylglyceride acyltransferase 1 activity via in vitro screening and a parallel, randomized, blinded, placebo-controlled clinical trial

Fig. 5

Baseline (fasting levels) subtracted change in serum TG levels following a HFM challenge after seven days of placebo or investigational product. a Baseline subtracted serum TG response over a 6 h period. GE significantly reduced the serum TG levels at 2 h (p = 0.014) and 4 h (p = (0.029) after the HFM compared to placebo. b AUC for the baseline subtracted serum TG was also significantly reduced by seven days of dietary GE (p = 0.021). Fasting serum TG = 95.8 ± 8.8; 94.7 ± 6.8; 90.3 ± 6.2; 102.1 ± 13.8; 103.8 ± 9.8 mg/dL, for placebo, APE, GE, RLE and ANE, respectively. Results are mean ± SEM. Comparisons between placebo and investigational product test groups were made using unpaired t-test (* P < 0.05)

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Nutrition & Metabolism

ISSN: 1743-7075

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