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Table 4 Day 1 and day 7 characteristics of participants completing the trial per protocol

From: Identification of a botanical inhibitor of intestinal diacylglyceride acyltransferase 1 activity via in vitro screening and a parallel, randomized, blinded, placebo-controlled clinical trial

Characteristics

Test Day

Placebo

APE

GE

RLE

ANE

N (Male/Female)

 

17 (9/8)

15 (7/8)

15 (6/9)

17 (6/11)

17 (11/6)

Age (years)

 

46.7 ± 9.9

47.0 ± 9.3

52.7 ± 12.6

46.8 ± 8.2

48.4 ± 9.0

Body Weight (kg)

1

90.8 ± 14.7

91.0 ± 10.4

88.3 ± 15.1

86.3 ± 13.6

87.9 ± 9.7

 

7

90.8 ± 14.7

91.1 ± 10.7

88.0 ± 15.3

86.3 ± 13.6

88.0 ± 9.6

BMI

1

30.2 ± 3.9

32.0 ± 1.8

30.8 ± 2.9

30.8 ± 3.5

30.4 ± 3.5

 

7

30.1 ± 3.9

32.0 ± 1.9

30.7 ± 3.0

30.5 ± 3.4

30.4 ± 3.5

Total Cholesterol (mg/dL)

1

206 ± 41

183 ± 30

190 ± 46

196 ± 34

200 ± 46

 

7

195 ± 44

170 ± 25

175 ± 35

191 ± 31

184 ± 35

LDL-C (mg/dL)

1

135 ± 42

116 ± 30

115 ± 42

123 ± 34

133 ± 43

 

7

129 ± 43

107 ± 25

105 ± 29

117 ± 34

119 ± 35

HDL-C (mg/dL)

1

50.3 ± 18.1

51.0 ± 17.2

58.7 ± 17.2

57.8 ± 17.7

50.1 ± 12.5

 

7

48.2 ± 19.4

46.3 ± 13.5

55.4 ± 19.8

54.8 ± 19.2

46.8 ± 11.2

TG (mg/dL)

1

97.5 ± 39.8

96.7 ± 39.8

101.7 ± 38.7

102.3 ± 35.8

111.1 ± 46.8

 

7

95.8 ± 36.2

94.7 ± 26.4

90.3 ± 23.8

102.1 ± 57

103.8 ± 40.4

  1. There were no statistically significant differences in any of the measured anthropometric or serum lipids between groups at day 1 or at day 7. Results are Mean ± SD