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Table 2 Effect of the low-fat diet analyzed with a repeated measures ANOVA test

From: Dietary restriction in obese children and its relation with eating behavior, fibroblast growth factor 21 and leptin: a prospective clinical intervention study

 

Basal

Two months after the dietary intervention

f

p-value

Mean ± SD

Mean ± SD

N = 45

N = 45

BMI (kg/m2)

28.75 ± 4.11

27.54 ± 4.10

22.67

<0.00002

WHR

0.95 ± 0.15

0.97 ± 0.06

0.48

0.49

Percent body fat

41.11 ± 3.83

40.69 ± 2.87

0.99

0.33

Glucose (mmol/l)

4.65 ± 0.47

4.74 ± 0.34

1.23

0.27

Triglycerides (mmol/l)

1.47 ± 0.61

1.47 ± 0.60

0.001

0.97

Total cholesterol (mmol/l)

4.03 ± 0.78

3.89 ± 0.75

2.52

0.12

HDL-cholesterol (mmol/l)

1.02 ± 0.21

1.14 ± 0.19

20.11

<0.00006

LDL-cholesterol (mmol/l)

2.26 ± 0.77

2.08 ± 0.71

6.55

<0.01

HOMA

6.04 ± 3.00

6.06 ± 2.93

0.01

0.93

Leptin (ng/ml)

27.94 ± 10.02

19.96 ± 10.62

24.75

<0.00001

Insulin (pmol/l)

200.22 ± 93.34

199.88 ± 96.26

0.002

0.97

Adiponectin (ng/ml)

15.10 ± 6.90

16.77 ± 9.35

1.54

0.22

FGF21 (pg/ml)

152.10 ± 97.07

112.59 ± 96.91

5.47

<0.02

Satiety responsiveness

11.17 ± 5.91

12.64 ± 4.30

3.46

0.07

Fussiness

10.26 ± 5.03

10.98 ± 4.92

1.53

0.22

Food responsiveness

11.64 ± 5.13

8.86 ± 4.57

13.64

<0.0006

Enjoyment of food

12.24 ± 2.65

10.55 ± 2.56

13.12

<0.0008

Desire to drink

8.88 ± 3.06

8.43 ± 22.86

0.80

0.38

Emotional undereating

6.24 ± 3.11

5.83 ± 3.15

2.66

0.11

Emotional overeating

6.88 ± 3.51

6.26 ± 3.19

1.48

0.23

  1. BMI Body mass index, WHR Waist-Height Ratio, HDL High density lipoprotein, LDL Low density lipoprotein, FGF21 Fibroblast growth factor 21