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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Moderate calorie restriction to achieve normal weight reverses β-cell dysfunction in diet-induced obese mice: involvement of autophagy

Fig. 5

Effects of CR on glucose-stimulated insulin secretion and insulin content in isolated islets. a glucose-stimulated insulin secretion was measured in isolated islets (10 islets per concentration in triplicates) at 2.8 and 16.7 mM glucose. b the stimulation index calculated by dividing insulin secretion in response to 16.7 mM glucose by that in response to 2.8 mM glucose. c insulin content of isolated islets was measured in batches of 5 islets in triplicates. Data were presented as means ± SE, n = 5 mice/group. a indicates P < 0.05 versus NC AL group; b indicates P < 0.05 versus HF AL group

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Nutrition & Metabolism

ISSN: 1743-7075

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