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Fig. 6 | Nutrition & Metabolism

Fig. 6

From: Moderate calorie restriction to achieve normal weight reverses β-cell dysfunction in diet-induced obese mice: involvement of autophagy

Fig. 6

Transmission electron microscopic evaluation of autophagosomes in β-cells of mice. The pancreas tail tissues were collected for TEM analysis. Granular cytoplasm or degenerated organelles surrounded by double membrane representing autophagosomes (white arrows) were seen in β-cells of NC CR, HF AL and HF → NC CR mice. Images were representative of all the experiments (n = 3), scale bars: 0.5 μm. Abbreviations: TEM, transmission electron microscopy; N, nucleus; M, mitochondria; IG, insulin granules

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Nutrition & Metabolism

ISSN: 1743-7075

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