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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1

Fig. 2

Effect of quercetin on expression of HO-1 and/or mitochondrial biogenesis markers in HFD-fed obese mice. Livers were isolated from mice fed a regular diet (RD), a high-fat diet (HFD), an HFD supplemented with 0.05 % quercetin (HF + 0.05 % Que) or 0.1 % quercetin (HFD + 0.1 % Que) for 9 weeks (n = 6 per group). a Expression of Nrf-2 and HO-1 mRNAs was quantified by real-time PCR. b Levels of HO-1 protein were determined by Western blotting. c Expression of PGC-1α, Nrf-1, and Tfam mRNAs was quantified by real-time PCR. d Levels of COX IV protein were determined by Western blotting. Data are mean ± SEM of six mice per group. *p < 0.05, **p < 0.01 versus HFD

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